Thalassaemia is a diverse group of genetic disorders with a worldwide distribution affecting
globin chain synthesis. The pathogenesis of thalassaemia lies in the unbalanced globin …

Thalassemia is a group of autosomal recessive hemoglobinopathies affecting the production
of normal alpha-or beta-globin chains that comprise hemoglobin. Ineffective production of …

Thalassemia management has reached new milestones, with new therapies promising the
dawning of a new era. However, conventional and new approaches require accessibility …

Sickle cell disease (SCD) is an inherited monogenic disorder with high prevalence
throughout sub-Saharan Africa, the Mediterranean basin, the Middle East, and India …

Background β-thalassaemia major poses a substantial economic burden, especially in
adults. We aimed to estimate the economic burden of adult patients with β-thalassaemia …

Background Both diagnosis and treatment of hemoglobinopathies have been associated
with an increased risk of fertility impairment. German guidelines recommend annual …

Hemoglobinopathies are the most common monogenic disorders in humans; among them,
thalassemia constitutes a serious medical and public health problem in high prevalence …

Thalassaemia is one of the most prevalent inherited blood disorders in Indonesia, with
highly diverse mutations ranging from mild to severe that can be found across the nation …

According to Lilienfeld, 1 epidemiology is the study of the distribution of a disease or a
physiological condition in the human population and the factors that influence this …

The four principles of Western medical bioethics, ie, autonomy, nonmaleficence,
beneficence and justice, published by Beauchamps and Childress in their seminal …