Gut microbiota-gonadal axis: the impact of gut microbiota on reproductive functions

VJ Ashonibare, BA Akorede, PJ Ashonibare… - Frontiers in …, 2024 - frontiersin.org
The influence of gut microbiota on physiological processes is rapidly gaining attention
globally. Despite being under-studied, there are available data demonstrating a gut …

Pathophysiology and management of testicular ischemia/reperfusion injury: Lessons from animal models

RE Akhigbe, AF Odetayo, TM Akhigbe, MA Hamed… - Heliyon, 2024 - cell.com
Testicular torsion is a urological emergency that involves the twisting of the spermatic cord
along its course. Compelling pieces of evidence have implicated oxidative stress-sensitive …

Ameliorative effects of sinapic acid against vancomycin-induced testicular oxidative damage, apoptosis, inflammation, testicular histopathologic disorders and …

SA Akarsu, M İleritürk, S Küçükler, N Akaras… - Reproductive …, 2024 - Elsevier
In this study, it was aimed to determine the effect of sinapic acid (SNP), a polyphenol with
antioxidant, anti-inflammatory and antibacterial properties, on testicular damage caused by …

Omega-3 fatty acid ameliorates bisphenol F-induced testicular toxicity by modulating Nrf2/NFkB pathway and apoptotic signaling

AF Odetayo, WJ Adeyemi, LA Olayaki - Frontiers in Endocrinology, 2023 - frontiersin.org
Introduction Bisphenol F (BPF) has been shown to disrupt testicular functions via
perturbation of testicular redox balance, while omega-3 fatty acid (O3FA) has been …

Naringin prevents diabetic-induced dysmetabolism in male wistar rats by modulating GSK-3 activities and oxidative stress-dependent pathways

KB Okesina, AF Odetayo, WJ Adeyemi… - Cell biochemistry and …, 2024 - Springer
Type 2 diabetes mellitus (T2DM), characterized by insulin resistance and glucose
dysmetabolism, is a major metabolic disorder accompanied with health and financial …

Glutamine alleviates I/R-Induced intestinal injury and dysmotility via the downregulation of xanthine oxidase/uric acid signaling and lactate generation in wistar rats

RE Akhigbe, BOA Aminat, TM Akhigbe… - Journal of Surgical …, 2024 - Elsevier
Introduction Disruption of intestinal histoarchitecture and intestinal dysmotility is critical to
intestinal ischemia/reperfusion (IR) injury and xanthine oxidase (XO)/uric acid (UA) signaling …

Omega 3 fatty acids preserve testicular function by ameliorating BPF-induced dysthyroidism: role of p53/Bcl-2 signaling and proton pump activities

AF Odetayo, LA Olayaki - JBRA assisted reproduction, 2024 - pmc.ncbi.nlm.nih.gov
Objective Bisphenol F (BPF) is an endocrinedisrupting chemical, but information about its
effect on thyroid hormones has not been fully explored. Omega 3 fatty acids (O3FA), on the …

Zinc ameliorates acrylamide-induced oxidative stress and apoptosis in testicular cells via Nrf2/HO-1/NfkB and Bax/Bcl2 signaling pathway

AJ Ajibare, AF Odetayo, OO Akintoye, LA Olayaki - Redox Report, 2024 - Taylor & Francis
Background: Acrylamide is a toxic substance formed in some foods that require high-
temperature cooking processes and has been implicated as a gonadotoxic agent. Zinc, on …

Naringin from sweet orange peel improves testicular function in high fat diet-induced diabetic rats by modulating xanthine oxidase/uric acid signaling and maintaining …

KB Okesina, AF Odetayo, WJ Adeyemi… - Laboratory Animal …, 2024 - Springer
Background Type 2 diabetes mellitus (T2DM) is a metabolic disorder affecting many organs,
including the testis. Naringin from orange peel extract (OPE) is a flavanone with fertility …

[HTML][HTML] The role of mannitol and vitamin D in ovarian ischemia/reperfusion injury in rats with acute abdominal

F Karateke, A Karateke, B Topdagi, M Atilgan… - Current Issues in …, 2024 - mdpi.com
This study was designed to investigate the effects of vitamin D and mannitol in an
experimental rat ovarian torsion model. Thirty-two female Wistar albino rats were randomly …