Zebrafish: a model system for the study of eye genetics

JM Fadool, JE Dowling - Progress in retinal and eye research, 2008 - Elsevier
Over the last decade, the use of the zebrafish as a genetic model has moved beyond the
proof-of-concept for the analysis of vertebrate embryonic development to demonstrated …

Technology for high-throughput screens: the present and future using zebrafish

DR Love, FB Pichler, A Dodd, BR Copp… - Current opinion in …, 2004 - Elsevier
The zebrafish is a popular vertebrate model organism with similar organ systems and gene
sequences to humans. Zebrafish embryos are optically transparent enabling organ …

[图书][B] The toxicology of fishes

RT Di Giulio, DE Hinton - 2008 - taylorfrancis.com
When looking for a book on fish toxicology, you might find one that discusses the
biochemical and molecular aspects, or one that focuses aquatic toxicology in general. You …

[HTML][HTML] Intraflagellar transport genes are essential for differentiation and survival of vertebrate sensory neurons

M Tsujikawa, J Malicki - Neuron, 2004 - cell.com
Cilia play diverse roles in vertebrate and invertebrate sensory neurons. We show that a
mutation of the zebrafish oval (ovl) locus affects a component of the ciliary transport (IFT) …

elipsa is an early determinant of ciliogenesis that links the IFT particle to membrane-associated small GTPase Rab8

Y Omori, C Zhao, A Saras, S Mukhopadhyay, W Kim… - Nature cell …, 2008 - nature.com
The formation and function of cilia involves the movement of intraflagellar transport (IFT)
particles underneath the ciliary membrane, along axonemal microtubules,. Although this …

Mutations in B3GALNT2 cause congenital muscular dystrophy and hypoglycosylation of α-dystroglycan

E Stevens, KJ Carss, S Cirak, AR Foley, S Torelli… - The American Journal of …, 2013 - cell.com
Mutations in several known or putative glycosyltransferases cause glycosylation defects in α-
dystroglycan (α-DG), an integral component of the dystrophin glycoprotein complex. The …

Oko meduzy and related crumbs genes are determinants of apical cell features in the vertebrate embryo

Y Omori, J Malicki - Current biology, 2006 - cell.com
Background Polarity is an essential attribute of most eukaryotic cells. One of the most
prominent features of cell polarity in many tissues is the subdivision of cell membrane into …

Fishing for gene function–endocrine modelling in the zebrafish

IM McGonnell, RC Fowkes - Journal of Endocrinology, 2006 - joe.bioscientifica.com
The use of zebrafish (Danio rerio) in scientific research is growing rapidly. It initially became
popular as a model of vertebrate development because zebrafish embryos develop rapidly …

Pharmacology and toxicology of pahayokolide A, a bioactive metabolite from a freshwater species of Lyngbya isolated from the Florida Everglades

JP Berry, M Gantar, RE Gawley, M Wang… - … and Physiology Part C …, 2004 - Elsevier
The genus of filamentous cyanobacteria, Lyngbya, has been found to be a rich source of
bioactive metabolites. However, identification of such compounds from Lyngbya has largely …

[HTML][HTML] Zebrafish N-cadherin, encoded by the glass onion locus, plays an essential role in retinal patterning

J Malicki, H Jo, Z Pujic - Developmental biology, 2003 - Elsevier
Genetic screens in zebrafish identified several loci that play essential roles in the patterning
of retinal architecture. Here, we show that one of them, glass onion, encodes the N-cadherin …