The Transforming Growth Factor-beta (TGF-β) family plays relevant roles in the regulation of
different cellular processes that are essential for tissue and organ homeostasis. In the case …

Liver fibrosis is a dynamic wound-healing process characterized by the net accumulation of
extracellular matrix. There is no efficient antifibrotic therapy other than liver transplantation to …

The Banff Working Group on Liver Allograft Pathology reviewed and discussed literature
evidence regarding antibody-mediated liver allograft rejection at the 11th (Paris, France …

Liver fibrosis is a serious health problem worldwide, which can be induced by a wide
spectrum of chronic liver injuries. However, until today, there is no effective therapy available …

Background and Aims In clinical and experimental NASH, the origin of the scar‐forming
myofibroblast is the HSC. We used foz/foz mice on a Western diet to characterize in detail …

Animal testing is still the most popular preclinical assessment model for liver fibrosis. To
develop efficient anti-fibrotic therapies, robust and representative in vitro models are …

Hepatitis B virus X protein (HBx) and hepatic stellate cells (HSCs) are critical for liver fibrosis
development. Anti-fibrosis occurs via reversion to quiescent-type HSCs or clearance of …

Background & Aims Serum microRNA (miRNA) levels are known to change in non-alcoholic
fatty liver disease (NAFLD) and may serve as useful biomarkers. This study aimed to profile …

Hepatic fibrosis (HF) is the pathological component of a variety of chronic liver diseases.
Hepatic stellate cells (HSC) are the main collagen-producing cells in the liver and their …

Liver fibrosis results from many chronic injuries and often progresses to cirrhosis, liver
failure, portal hypertension, and hepatocellular carcinoma. Liver transplantation is the only …