Oligo-and poly-nucleotides: 50 years of chemical synthesis
CB Reese - Organic & biomolecular chemistry, 2005 - pubs.rsc.org
It is fifty years since the first chemical synthesis of a dinucleoside phosphate and a
dinucleotide with natural 3′→ 5′-internucleotide linkages was reported. The main …
dinucleotide with natural 3′→ 5′-internucleotide linkages was reported. The main …
Recent advances in tetrazole chemistry
RN Butler - Advances in Heterocyclic Chemistry, 1977 - Elsevier
Publisher Summary This chapter discusses the development of tetrazole chemistry from
1965 to 1975. Over the years, it has been noted that the field has grown rapidly, with regard …
1965 to 1975. Over the years, it has been noted that the field has grown rapidly, with regard …
Screening λgt recombinant clones by hybridization to single plaques in situ
WD Benton, RW Davis - Science, 1977 - science.org
ScreeningXgtRecombinant Clones by Hybridization to Single Plaques in situ Page 1 (R.
Rodriguez, F. Bolivar, H. Goodman, H. Boyer, and M. Betlach, personal communication). Hencei …
Rodriguez, F. Bolivar, H. Goodman, H. Boyer, and M. Betlach, personal communication). Hencei …
The chemical synthesis of oligo-and poly-nucleotides by the phosphotriester approach
CB Reese - Tetrahedron, 1978 - Elsevier
(DNA), arc derived from the saox lmsa (4, s ad 6, rupcctively) aat&eeofthcabove-buttbc otk
pridpd zdeoxyfibooIKkuai&, thymidine, ic the l-/3-MQk! oxyrMundi of thymine Jb.! 3ofar …
pridpd zdeoxyfibooIKkuai&, thymidine, ic the l-/3-MQk! oxyrMundi of thymine Jb.! 3ofar …
DNA synthesis
SA Narang - Tetrahedron, 1983 - Elsevier
Synthetic strategy CHEMICALSYNTHESIS.......................................... 5 Historical background
(i) Phosphodiester approach (ii) Phosphotriester approach (iii) Modified phosphotriester …
(i) Phosphodiester approach (ii) Phosphotriester approach (iii) Modified phosphotriester …
Chemical synthesis of oligonucleotides
V Amarnath, AD Broom - Chemical Reviews, 1977 - ACS Publications
Ribo-and deoxyribooligonucleotides are of interest both be-cause of their biological
significance and for the challenge they present to the synthetic organic chemist. The …
significance and for the challenge they present to the synthetic organic chemist. The …
Reaction between 1-arenesulphonyl-3-nitro-1, 2, 4-triazoles and nucleoside base residues. Elucidation of the nature of side-reactions during oligonucleotide …
CB Reese, A Ubasawa - Tetrahedron Letters, 1980 - Elsevier
The protected guanosine and uridine derivatives (3a, 3b and 4) react with 1-(mesitylene-2-
sulphonyl)-3-nitro-1, 2, 4-triazole (MSNT, 2a) to give 5a, 5b and 7, respectively: 9 is …
sulphonyl)-3-nitro-1, 2, 4-triazole (MSNT, 2a) to give 5a, 5b and 7, respectively: 9 is …
The protection of uracil and guanine residues in oligonucleotide synthesis
SS Jones, CB Reese, S Sibanda, A Ubasawa - Tetrahedron Letters, 1981 - Elsevier
The protection of uracil and 2-N-acyl guanine residues with 4-O-phenyl [or 4-O-(2, 4-
dimethylphenyl)] and 6-O-(2-nitrophenyl) groups as in 7a [or 7b] and 9, respectively, is …
dimethylphenyl)] and 6-O-(2-nitrophenyl) groups as in 7a [or 7b] and 9, respectively, is …
Six base oligonucleotide linkers and methods for their use
F Barany - US Patent 4,719,179, 1988 - Google Patents
BACKGROUND OF THE INVENTION A. Field Of The Invention This invention relates to
recombinant-DNA technol ogy. More speci? cally, it relates to linkers which can be used to …
recombinant-DNA technol ogy. More speci? cally, it relates to linkers which can be used to …
Arylsulfonyltetrazoles, new coupling reagents and further improvements in the triester method for the synthesis of deoxyribooligonucleotides1
J Stawinski, T Hozumi, SA Narang… - Nucleic Acids …, 1977 - academic.oup.com
The modified triester approach has been further improved and refined to the synthesis of
defined sequences of deoxyribooligonucleotides. Improvements include …
defined sequences of deoxyribooligonucleotides. Improvements include …