[HTML][HTML] Microfluidics integrated biosensors: A leading technology towards lab-on-a-chip and sensing applications

G Luka, A Ahmadi, H Najjaran, E Alocilja, M DeRosa… - Sensors, 2015 - mdpi.com
A biosensor can be defined as a compact analytical device or unit incorporating a biological
or biologically derived sensitive recognition element immobilized on a physicochemical …

[HTML][HTML] Small-molecule binding aptamers: Selection strategies, characterization, and applications

A Ruscito, MC DeRosa - Frontiers in chemistry, 2016 - frontiersin.org
Aptamers are single-stranded, synthetic oligonucleotides that fold into 3-dimensional
shapes capable of binding non-covalently with high affinity and specificity to a target …

Advances in aptamers, and application of mycotoxins detection: A review

Y Fan, J Li, K Amin, H Yu, H Yang, Z Guo… - Food Research …, 2023 - Elsevier
Mycotoxin contamination in food products can easily cause serious health hazards and
economic losses to human beings. How to accurately detect and effectively control …

[HTML][HTML] Recent advances in quantum dots-based biosensors for antibiotics detection

R Ding, Y Chen, Q Wang, Z Wu, X Zhang, B Li… - Journal of …, 2022 - Elsevier
Antibiotics are a category of chemical compounds used to treat bacterial infections and are
widely applied in cultivation, animal husbandry, aquaculture, and pharmacy. Currently …

[HTML][HTML] Chemical modification of aptamers for increased binding affinity in diagnostic applications: Current status and future prospects

JP Elskens, JM Elskens, A Madder - International journal of molecular …, 2020 - mdpi.com
Aptamers are short single stranded DNA or RNA oligonucleotides that can recognize
analytes with extraordinary target selectivity and affinity. Despite their promising properties …

[HTML][HTML] Selection and biosensor application of aptamers for small molecules

F Pfeiffer, G Mayer - Frontiers in chemistry, 2016 - frontiersin.org
Small molecules play a major role in the human body and as drugs, toxins, and chemicals.
Tools to detect and quantify them are therefore in high demand. This review will give an …

Nucleic acid aptamer-based methods for diagnosis of infections

KS Park - Biosensors and Bioelectronics, 2018 - Elsevier
Infectious diseases are a serious global problem, which not only take an enormous human
toll but also incur tremendous economic losses. In combating infectious diseases, rapid and …

Assays to estimate the binding affinity of aptamers

R Thevendran, M Citartan - Talanta, 2022 - Elsevier
Aptamers have become coming-of-age molecular recognition elements in both diagnostic
and therapeutic applications. Generated by SELEX, the 'quality control'of aptamers, which …

Comprehensive analytical comparison of strategies used for small molecule aptamer evaluation

M McKeague, A De Girolamo, S Valenzano… - Analytical …, 2015 - ACS Publications
Nucleic acid aptamers are versatile molecular recognition agents that bind to their targets
with high selectivity and affinity. The past few years have seen a dramatic increase in …

[HTML][HTML] Blueprints for biosensors: design, limitations, and applications

AC Carpenter, IT Paulsen, TC Williams - Genes, 2018 - mdpi.com
Biosensors are enabling major advances in the field of analytics that are both facilitating and
being facilitated by advances in synthetic biology. The ability of biosensors to rapidly and …