The structure and function of the endothelial glycocalyx layer

S Weinbaum, JM Tarbell… - Annu. Rev. Biomed. Eng …, 2007 - annualreviews.org
Over the past decade, since it was first observed in vivo, there has been an explosion in
interest in the thin (∼ 500 nm), gel-like endothelial glycocalyx layer (EGL) that coats the …

The endothelial surface layer

AR Pries, TW Secomb, P Gaehtgens - Pflügers Archiv, 2000 - Springer
The endothelial lining of blood vessels presents a large surface area for exchange of
materials between blood and tissues, and is critically involved in many other processes such …

[图书][B] Handbook of porous media

K Vafai - 2015 - books.google.com
This third edition offers a comprehensive overview of the latest theories on flow, transport,
and heat-exchange processes in porous media. It also details sophisticated porous media …

Endothelial glycocalyx shedding and vascular permeability in severely injured trauma patients

E Rahbar, JC Cardenas, G Baimukanova… - Journal of translational …, 2015 - Springer
Background The endothelial glycocalyx layer (EGL) is a key regulator of vascular
permeability, cell adhesion, and inflammation. The EGL is primarily composed of syndecan …

Heparan sulfate proteoglycan is a mechanosensor on endothelial cells

JA Florian, JR Kosky, K Ainslie, Z Pang… - Circulation …, 2003 - Am Heart Assoc
The objective of this study was to test whether a glycosaminoglycan component of the
surface glycocalyx layer is a fluid shear stress sensor on endothelial cells (ECs). Because …

The endothelial glycocalyx protects against myocardial edema

BM van den Berg, H Vink, JAE Spaan - Circulation research, 2003 - Am Heart Assoc
Myocardial tissue edema attributable to increased microvascular fluid loss contributes to
cardiac dysfunction after myocardial ischemia, cardiopulmonary bypass, hypertension, and …

Endothelial glycocalyx: permeability barrier and mechanosensor

FE Curry, RH Adamson - Annals of biomedical engineering, 2012 - Springer
Endothelial cells are covered with a polysaccharide rich layer more than 400 nm thick,
mechanical properties of which limit access of circulating plasma components to endothelial …

Regulation and function of endothelial glycocalyx layer in vascular diseases

I Sieve, AK Münster-Kühnel, D Hilfiker-Kleiner - Vascular pharmacology, 2018 - Elsevier
In the vascular system, the endothelial surface layer (ESL) as the inner surface of blood
vessels affects mechanotransduction, vascular permeability, rheology, thrombogenesis, and …

Oxidized lipoproteins degrade the endothelial surface layer: implications for platelet-endothelial cell adhesion

H Vink, AA Constantinescu, JAE Spaan - Circulation, 2000 - Am Heart Assoc
Background—Flowing erythrocytes and platelets are separated from the luminal endothelial
cell (EC) surface by a 0.5-μm-wide space named the endothelial surface layer. We …

Damage of the endothelial glycocalyx in dialysis patients

CA Vlahu, BA Lemkes, DG Struijk… - Journal of the …, 2012 - journals.lww.com
Damage to the endothelial glycocalyx, which helps maintain vascular homeostasis,
heightens the sensitivity of the vasculature to atherogenic stimuli. Patients with renal failure …