Nuclear pore complexes (NPCs) are large channels spanning the nuclear envelope that
mediate nucleocytoplasmic transport. They are composed of multiple copies of~ 30 proteins …

Lamin B receptor (LBR) is an integral protein of the inner nuclear membrane, containing a
hydrophilic N-terminal end protruding into the nucleoplasm, eight hydrophobic segments …

The nuclear pore complex (NPC) tethers chromatin to create an environment for gene
regulation, but little is known about how this activity is regulated to avoid excessive tethering …

Nuclear pore complexes mediate the transport between the cell nucleoplasm and
cytoplasm. These 125 MDa structures are among the largest assemblies found in …

Dictyostelium cells undergo a semi-closed mitosis, during which the nuclear envelope (NE)
persists; however, free diffusion between the cytoplasm and the nucleus takes place. To …

The subcellular compartmentalisation of eukaryotic cells requires selective exchange
between the cytoplasm and the nucleus. Intact nucleocytoplasmic transport is vital for normal …

Nuclear pore complexes (NPCs) form the gateway to the nucleus, mediating virtually all
nucleocytoplasmic trafficking. Assembly of a nuclear pore complex requires the organization …

Abstract Background Nuclear pore complexes (NPCs) are sophisticated and dynamic
protein structures that straddle the nuclear envelope and act as gatekeepers for transporting …

In metazoans with “open” mitosis, cells undergo structural changes involving the complete
disassembly of the nuclear envelope (NE). In post-mitosis, the dividing cell faces the …

Nucleoporins have been reported to regulate pluripotent biology, but how they do so
remains partially characterized. This study examined the effects of nup155 gene disruption …