Molecular rotors: fluorescent sensors for microviscosity and conformation of biomolecules

M Paez‐Perez, MK Kuimova - Angewandte Chemie, 2024 - Wiley Online Library
The viscosity and crowding of biological environment are considered vital for the correct
cellular function, and alterations in these parameters are known to underly a number of …

Supramolecular self-assembly to control structural and biological properties of multicomponent hydrogels

BO Okesola, Y Wu, B Derkus, S Gani, D Wu… - Chemistry of …, 2019 - ACS Publications
Self-assembled nanofibers are ubiquitous in nature and serve as inspiration for the design
of supramolecular hydrogels. A multicomponent approach offers the possibility of enhancing …

Controlling the assembly and properties of low-molecular-weight hydrogelators

ER Draper, DJ Adams - Langmuir, 2019 - ACS Publications
Low-molecular-weight gels are formed by the self-assembly of small molecules into fibrous
networks that can immobilize a significant amount of solvent. Here, we focus on our work …

Applications of microscopy and small angle scattering techniques for the characterisation of supramolecular gels

CRM MacDonald, ER Draper - Beilstein Journal of Organic …, 2024 - beilstein-journals.org
When evaluating soft self-assembling materials for use in any application, the structural or
morphological characterisation is highly important. We know that the hierarchal molecular …

Designing Cardin-Motif Peptide and Heparin-Based Multicomponent Advanced Bioactive Hydrogel Scaffolds to Control Cellular Behavior

S Sen, P Sharma, VK Pal, S Roy - Biomacromolecules, 2023 - ACS Publications
Recently, peptide and sugar-based multicomponent systems have gained much interest in
attaining the sophisticated structure and biofunctional complexity of the extracellular matrix …

Effects of amyloid-β-mimicking peptide hydrogel matrix on neuronal progenitor cell phenotype

TG Mathes, M Monirizad, M Ermis, NR de Barros… - Acta Biomaterialia, 2024 - Elsevier
Self-assembling peptide-based hydrogels have become a highly attractive scaffold for three-
dimensional (3D) in vitro disease modeling as they provide a way to create tunable matrices …

Controlling the network type in self-assembled dipeptide hydrogels

C Colquhoun, ER Draper, R Schweins, M Marcello… - Soft Matter, 2017 - pubs.rsc.org
We show that the same low molecular weight gelator can form gels using three different
methods. Gels were formed from a high pH solution either by adding a salt or by adding an …

Inducing differential self-assembling behavior in ultrashort peptide hydrogelators using simple metal salts

P Sharma, H Kaur, S Roy - Biomacromolecules, 2019 - ACS Publications
Controlling the self-assembly pathways can be an effective means to create complex
multifunctional structures based on a single gelator design. To this direction, an ion …

Supramolecular ultra-short carboxybenzyl-protected dehydropeptide-based hydrogels for drug delivery

SRS Veloso, PJ Jervis, JFG Silva, L Hilliou… - Materials Science and …, 2021 - Elsevier
Self-assembled peptide-based hydrogels are promising materials for biomedical research
owing to biocompatibility and similarity to the extracellular matrix, amenable synthesis and …

Supramolecular nucleoside-based gel: molecular dynamics simulation and characterization of its nanoarchitecture and self-assembly mechanism

MGF Angelerou, PWJM Frederix, M Wallace, B Yang… - Langmuir, 2018 - ACS Publications
Among the diversity of existing supramolecular hydrogels, nucleic acid-based hydrogels are
of particular interest for potential drug delivery and tissue engineering applications because …