The gastrointestinal tract plays a role in the development and treatment of metabolic
diseases. During a meal, the gut provides crucial information to the brain regarding …

The complex bidirectional communication between the gut and the brain is finely
orchestrated by different systems, including the endocrine, immune, autonomic, and enteric …

Ghrelin, a gastric-derived acylated peptide, regulates energy homeostasis by transmitting
information about peripheral nutritional status to the brain, and is essential for protecting …

The brain is the key organ of the response to stress because it determines what is
threatening and, therefore, potentially stressful, as well as the physiological and behavioral …

Leptin and ghrelin are two hormones that have been recognized to have a major influence
on energy balance. Leptin is a mediator of long‐term regulation of energy balance …

The gastrointestinal peptide hormone ghrelin stimulates appetite in rodents and humans via
hypothalamic actions. We discovered expression of ghrelin in a previously uncharacterized …

Background: Recent studies point to the adipose tissue as a highly active endocrine organ
secreting a range of hormones. Leptin, ghrelin, adiponectin, and resistin are considered to …

Ghrelin is a peptide predominantly produced by the stomach. Ghrelin displays strong GH-
releasing activity. This activity is mediated by the activation of the so-called GH …

The gut hormone and neuropeptide ghrelin affects energy balance and growth hormone
release through hypothalamic action that involves synaptic plasticity in the melanocortin …

Ghrelin is brain-gut peptide with growth hormone-releasing and appetite-inducing activities.
It is mainly secreted from the stomach mucosa but it is also expressed widely in different …