Endothelium structure and function in kidney health and disease

N Jourde-Chiche, F Fakhouri, L Dou, J Bellien… - Nature Reviews …, 2019 - nature.com
The kidney harbours different types of endothelia, each with specific structural and functional
characteristics. The glomerular endothelium, which is highly fenestrated and covered by a …

Mesenchymal stromal cells: current understanding and clinical status

HK Salem, C Thiemermann - Stem cells, 2010 - academic.oup.com
Multipotent mesenchymal stromal cells (MSCs) represent a rare heterogeneous subset of
pluripotent stromal cells that can be isolated from many different adult tissues that exhibit the …

Chronic kidney disease: the global challenge

AM El Nahas, AK Bello - The lancet, 2005 - thelancet.com
The worldwide rise in the number of patients with chronic kidney disease (CKD) and
consequent end-stage renal failure necessitating renal replacement therapy is threatening …

Conditioned media from mesenchymal stem cells enhanced bone regeneration in rat calvarial bone defects

M Osugi, W Katagiri, R Yoshimi, T Inukai… - … engineering part A, 2012 - liebertpub.com
Tissue engineering has recently become available as a treatment procedure for bone
augmentation. However, this procedure has several problems, such as high capital …

Macrophage diversity in renal injury and repair

SD Ricardo, H Van Goor, AA Eddy - The Journal of clinical …, 2008 - Am Soc Clin Investig
Monocyte-derived macrophages can determine the outcome of the immune response and
whether this response contributes to tissue repair or mediates tissue destruction. In addition …

Mesenchymal stem cells are renotropic, helping to repair the kidney and improve function in acute renal failure

M Morigi, B Imberti, C Zoja, D Corna… - Journal of the …, 2004 - journals.lww.com
Injury to a target organ can be sensed by bone marrow stem cells that migrate to the site of
damage, undergo differentiation, and promote structural and functional repair. This …

Mechanisms of progression and regression of renal lesions of chronic nephropathies and diabetes

G Remuzzi, A Benigni, A Remuzzi - The Journal of clinical …, 2006 - Am Soc Clin Investig
The incidence of chronic kidney diseases is increasing worldwide, and these conditions are
emerging as a major public health problem. While genetic factors contribute to susceptibility …

Plasticity of marrow-derived stem cells

EL Herzog, L Chai, DS Krause - Blood, 2003 - ashpublications.org
Bone marrow (BM) contains hematopoietic stem cells (HSCs), which differentiate into every
type of mature blood cell; endothelial cell progenitors; and marrow stromal cells, also called …

Recruitment of podocytes from glomerular parietal epithelial cells

D Appel, DB Kershaw, B Smeets, G Yuan… - Journal of the …, 2009 - journals.lww.com
Loss of a critical number of podocytes from the glomerular tuft leads to glomerulosclerosis.
Even in health, some podocytes are lost into the urine. Because podocytes themselves …

A side order of stem cells: the SP phenotype

GA Challen, MH Little - Stem cells, 2006 - academic.oup.com
A defining property of murine hematopoietic stem cells (HSCs) is low fluorescence after
staining with Hoechst 33342 and Rhodamine 123. These dyes have proven to be …