Increasing evidence indicates that non-DNA sequence-based epigenetic information can be
inherited across several generations in organisms ranging from yeast to plants to humans …

A remarkable epigenetic remodelling process occurs shortly after fertilization, which restores
totipotency to the zygote. This involves global DNA demethylation, chromatin remodelling …

Abstract Background Long non-coding RNAs (lncRNAs) have a size of more than 200 bp
and are known to regulate a host of crucial cellular processes like proliferation …

A significant proportion of mammalian genomes corresponds to genes that transcribe long
non-coding RNAs (lncRNAs). Throughout the last decade, the number of studies concerning …

There is a growing body of evidence linking maternal overnutrition to obesity and
psychopathology that can be conserved across multiple generations. Recently, we …

Epigenetic transgenerational inheritance of disease and phenotypic variation can be
induced by several toxicants, such as vinclozolin. This phenomenon can involve DNA …

Having been debated for many years, the presence and role of spermatozoal RNAs is
resolving, and their contribution to development is now appreciated. Data from different …

Epidemiological studies provide strong evidence for the impact of diverse paternal life
experiences on offspring neurodevelopmental disease risk. While these associations are …

Two of the most prevalent ovarian diseases affecting women's fertility and health are Primary
Ovarian Insufficiency (POI) and Polycystic Ovarian Syndrome (PCOS). Previous studies …

The paternal contribution to the new individual is not just limited to half the diploid genome.
Recent findings have shown that sperm delivers to the oocyte several components …