Viscoelastic cell microenvironment: hydrogel‐based strategy for recapitulating dynamic ECM mechanics

Y Ma, T Han, Q Yang, J Wang, B Feng… - Advanced Functional …, 2021 - Wiley Online Library
The native extracellular matrix (ECM) generally exhibits dynamic mechanical properties and
displays time‐dependent responses to deformation or mechanical loading, in terms of …

Physical biology of human brain development

S Budday, P Steinmann, E Kuhl - Frontiers in cellular neuroscience, 2015 - frontiersin.org
Neurodevelopment is a complex, dynamic process that involves a precisely orchestrated
sequence of genetic, environmental, biochemical, and physical events. Developmental …

Mechanical properties of gray and white matter brain tissue by indentation

S Budday, R Nay, R De Rooij, P Steinmann… - Journal of the …, 2015 - Elsevier
The mammalian brain is composed of an outer layer of gray matter, consisting of cell bodies,
dendrites, and unmyelinated axons, and an inner core of white matter, consisting primarily of …

Brain stiffness increases with myelin content

J Weickenmeier, R de Rooij, S Budday, P Steinmann… - Acta biomaterialia, 2016 - Elsevier
Brain stiffness plays an important role in neuronal development and disease, but reported
stiffness values vary significantly for different species, for different brains, and even for …

[HTML][HTML] The role of mechanics during brain development

S Budday, P Steinmann, E Kuhl - Journal of the Mechanics and Physics of …, 2014 - Elsevier
Convolutions are a classical hallmark of most mammalian brains. Brain surface morphology
is often associated with intelligence and closely correlated with neurological dysfunction …

Brain neurotrauma: molecular, neuropsychological, and rehabilitation aspects

FH Kobeissy - 2015 - books.google.com
With the contribution from more than one hundred CNS neurotrauma experts, this book
provides a comprehensive and up-to-date account on the latest developments in the area of …

Constitutive modeling of brain tissue: current perspectives

R de Rooij, E Kuhl - Applied Mechanics Reviews, 2016 - asmedigitalcollection.asme.org
Modeling the mechanical response of the brain has become increasingly important over the
past decades. Although mechanical stimuli to the brain are small under physiological …

Tissue mechanics, an important regulator of development and disease

NME Ayad, S Kaushik… - … Transactions of the …, 2019 - royalsocietypublishing.org
A growing body of work describes how physical forces in and around cells affect their
growth, proliferation, migration, function and differentiation into specialized types. How cells …

Magnetic resonance elastography (MRE) in cancer: Technique, analysis, and applications

KM Pepin, RL Ehman, KP McGee - Progress in nuclear magnetic resonance …, 2015 - Elsevier
Tissue mechanical properties are significantly altered with the development of cancer.
Magnetic resonance elastography (MRE) is a noninvasive technique capable of quantifying …

Mechanical properties of the spinal cord and brain: Comparison with clinical-grade biomaterials for tissue engineering and regenerative medicine

RD Bartlett, D Eleftheriadou, R Evans, D Choi… - Biomaterials, 2020 - Elsevier
Disorders affecting the central nervous system are a leading cause of disability in the world.
Regenerative medicine using biomaterial-based therapies is a growing field that has …