New applications of synthetic biology tools for cyanobacterial metabolic engineering

M Santos-Merino, AK Singh, DC Ducat - Frontiers in bioengineering …, 2019 - frontiersin.org
Cyanobacteria are promising microorganisms for sustainable biotechnologies, yet unlocking
their potential requires radical re-engineering and application of cutting-edge synthetic …

Biophotovoltaics: green power generation from sunlight and water

J Tschörtner, B Lai, JO Krömer - Frontiers in microbiology, 2019 - frontiersin.org
Biophotovoltaics is a relatively new discipline in microbial fuel cell research. The basic idea
is the conversion of light energy into electrical energy using photosynthetic microorganisms …

Pooled CRISPRi screening of the cyanobacterium Synechocystis sp PCC 6803 for enhanced industrial phenotypes

L Yao, K Shabestary, SM Björk… - Nature …, 2020 - nature.com
Cyanobacteria are model organisms for photosynthesis and are attractive for biotechnology
applications. To aid investigation of genotype-phenotype relationships in cyanobacteria, we …

Metabolomics-based engineering for biofuel and bio-based chemical production in microalgae and cyanobacteria: A review

Y Kato, K Inabe, R Hidese, A Kondo… - Bioresource Technology, 2022 - Elsevier
Metabolomics, an essential tool in modern synthetic biology based on the design-build-test-
learn platform, is useful for obtaining a detailed understanding of cellular metabolic …

Cyanobacteria as cell factories: the roles of host and pathway engineering and translational research

D Jaiswal, D Sahasrabuddhe, PP Wangikar - Current Opinion in …, 2022 - Elsevier
Highlights•Host organisms need to tolerate outdoor conditions and abiotic stresses.•Robust,
fast-growing cyanobacterial strains can be engineered as efficient hosts.•Engineered and …

Integrated biomolecular and bioprocess engineering strategies for enhancing the lipid yield from microalgae

B Behera, Y Unpaprom, R Ramaraj, GP Maniam… - … and Sustainable Energy …, 2021 - Elsevier
Algal biofuels have received wide attention in recent years for its potential to reduce the
dependence on conventional fossil fuels. Despite the portrayed advantages of high growth …

Deciphering and engineering photosynthetic cyanobacteria for heavy metal bioremediation

J Cui, Y Xie, T Sun, L Chen, W Zhang - Science of The Total Environment, 2021 - Elsevier
Environmental pollution caused by heavy metals has received worldwide attentions due to
their ubiquity, poor degradability and easy bioaccumulation in host cells. As one potential …

Metabolic engineering of Synechococcus elongatus 7942 for enhanced sucrose biosynthesis

B Wang, C Zuniga, MT Guarnieri, K Zengler… - Metabolic …, 2023 - Elsevier
The capability of cyanobacteria to produce sucrose from CO 2 and light has a remarkable
societal and biotechnological impact since sucrose can serve as a carbon and energy …

[HTML][HTML] Cycling between growth and production phases increases cyanobacteria bioproduction of lactate

K Shabestary, HP Hernández, R Miao, E Ljungqvist… - Metabolic …, 2021 - Elsevier
Decoupling growth from product synthesis is a promising strategy to increase carbon
partitioning and maximize productivity in cell factories. However, reduction in both substrate …

Towards model-driven characterization and manipulation of plant lipid metabolism

SM Correa, AR Fernie, Z Nikoloski, Y Brotman - Progress in lipid research, 2020 - Elsevier
Plant lipids have versatile applications and provide essential fatty acids in human diet.
Therefore, there has been a growing interest to better characterize the genetic basis …