Synopsis of guidelines for the clinical management of cerebral cavernous malformations: consensus recommendations based on systematic literature review by the …

A Akers, RAS Salman, IA Awad, K Dahlem… - …, 2017 - journals.lww.com
BACKGROUND: Despite many publications about cerebral cavernous malformations
(CCMs), controversy remains regarding diagnostic and management strategies …

Natural history of cerebral arteriovenous malformations: a meta-analysis

BA Gross, R Du - Journal of neurosurgery, 2013 - thejns.org
Object The purpose of this report was to provide overall arteriovenous malformation (AVM)
hemorrhage rates and, with enhanced statistical power, to elucidate significant risk factors …

Familial cerebral cavernous malformations

A Zafar, SA Quadri, M Farooqui, A Ikram, M Robinson… - Stroke, 2019 - Am Heart Assoc
surface interactions between these as well as with numerous binding partners. 17 FCCM is
inherited in an autosomal dominant fashion, with every affected parent having a 50 …

Cerebral cavernous malformation: what a practicing clinician should know

KD Flemming, G Lanzino - Mayo Clinic Proceedings, 2020 - Elsevier
Cavernous malformations (CMs) are angiographically occult, low-flow vascular
malformations of the central nervous system. They are acquired lesions, with approximately …

Hemorrhage from cerebral cavernous malformations: a systematic pooled analysis

BA Gross, R Du - Journal of Neurosurgery, 2017 - thejns.org
OBJECTIVE The aim of this paper is to define an overall cavernous malformation (CM)
hemorrhage rate and risk factors for hemorrhage. METHODS The authors performed a …

Cerebral cavernous malformations: from CCM genes to endothelial cell homeostasis

A Fischer, J Zalvide, E Faurobert, C Albiges-Rizo… - Trends in molecular …, 2013 - cell.com
Cerebral cavernous malformations (CCMs) are vascular lesions that can occur sporadically
or as a consequence of inherited loss-of-function mutations, predominantly in the genes …

Brainstem cavernous malformations: surgical results in 104 patients and a proposed grading system to predict neurological outcomes

RM Garcia, ME Ivan, MT Lawton - Neurosurgery, 2015 - journals.lww.com
BACKGROUND: Once considered inoperable lesions in inviolable territory, brainstem
cavernous malformations (BSCM) are now surgically curable with acceptable operative …

Surgical outcomes and natural history of intramedullary spinal cord cavernous malformations: a single-center series and meta-analysis of individual patient data

JH Badhiwala, F Farrokhyar, W Alhazzani… - … of Neurosurgery: Spine, 2014 - thejns.org
Object Information pertaining to the natural history of intramedullary spinal cord cavernous
malformations (ISCCMs) and patient outcomes after surgery is scarce. To evaluate factors …

Brainstem cavernous malformations: 1390 surgical cases from the literature

BA Gross, HH Batjer, IA Awad, BR Bendok, R Du - World neurosurgery, 2013 - Elsevier
Objective Although surgical resection of brainstem cavernous malformations (CM) has been
reviewed, numerous large surgical series have been recently reported. Methods Eighteen …

Exceptional aggressiveness of cerebral cavernous malformation disease associated with PDCD10 mutations

R Shenkar, C Shi, T Rebeiz, RA Stockton… - Genetics in …, 2015 - nature.com
Purpose: The phenotypic manifestations of cerebral cavernous malformation disease
caused by rare PDCD10 mutations have not been systematically examined, and a …