Understanding the contextual functions of C1q and LAIR-1 and their applications

M Son - Experimental & Molecular Medicine, 2022 - nature.com
The importance of the complement component C1q has been highlighted by its involvement
in autoimmunity, infection, inflammatory diseases, and tumors. The unique tulip-like structure …

Effects of electroactive materials on nerve cell behaviors and applications in peripheral nerve repair

Q Wang, H Wang, Y Ma, X Cao, H Gao - Biomaterials Science, 2022 - pubs.rsc.org
Peripheral nerve damage can lead to loss of function or even complete disability, which
brings about a huge burden on both the patient and society. Regulating nerve cell behavior …

An update on Ym1 and its immunoregulatory role in diseases

Q Kang, L Li, Y Pang, W Zhu, L Meng - Frontiers in Immunology, 2022 - frontiersin.org
Ym1 is a rodent-specific chitinase-like protein (CLP) lacking catalytic activity, whose cellular
origins are mainly macrophages, neutrophils and other cells. Although the detailed function …

Ti3C2Tx MXene-Coated Electrospun PCL Conduits for Enhancing Neurite Regeneration and Angiogenesis

LP Nan, Z Lin, F Wang, XH Jin, JQ Fang… - … in Bioengineering and …, 2022 - frontiersin.org
An electrical signal is the key basis of normal physiological function of the nerve, and the
stimulation of the electric signal also plays a very special role in the repair process of nerve …

Bidirectional crosstalk between the peripheral nervous system and lymphoid tissues/organs

A Boahen, D Hu, MJ Adams, PK Nicholls… - Frontiers in …, 2023 - frontiersin.org
The central nervous system (CNS) influences the immune system generally by regulating
the systemic concentration of humoral substances (eg, cortisol and epinephrine), whereas …

Implantation of a nerve protector embedded with human GMSC-derived Schwann-like cells accelerates regeneration of crush-injured rat sciatic nerves

Q Zhang, JC Burrell, J Zeng, FI Motiwala, S Shi… - Stem cell research & …, 2022 - Springer
Abstract Background Peripheral nerve injuries (PNIs) remain one of the great clinical
challenges because of their considerable long-term disability potential. Postnatal neural …

Exploring the physicochemical, electroactive, and biodelivery properties of metal nanoparticles on peripheral nerve regeneration

M Sharifi, MK Farahani, M Salehi, A Atashi… - ACS Biomaterials …, 2022 - ACS Publications
Despite the advances in the regeneration/rehabilitation field of damaged tissues, the
functional recovery of peripheral nerves (PNs), especially in a long gap injury, is considered …

Anti-inflammatory activity of synaptamide in the peripheral nervous system in a model of sciatic nerve injury

A Starinets, A Tyrtyshnaia, I Manzhulo - International Journal of Molecular …, 2023 - mdpi.com
N-docosahexaenoylethanolamine (DHEA), or synaptamide, is an endogenous metabolite of
docosahexaenoic acid (DHA) that exhibits synaptogenic and neurogenic effects. In our …

Ibuprofen‐loaded bilayer electrospun mesh modulates host response toward promoting full‐thickness abdominal wall defect repair

J Liu, R Tang, X Zhu, Q Ma, X Mo… - Journal of Biomedical …, 2024 - Wiley Online Library
Pro‐inflammatory response impairs the constructive repair of abdominal wall defects after
mesh implantation. Electrospinning‐aid functionalization has the potential to improve the …

Physical stimulation combined with biomaterials promotes peripheral nerve injury repair

Z Zeng, Y Yang, J Deng, M Saif Ur Rahman, C Sun… - Bioengineering, 2022 - mdpi.com
Peripheral nerve injury (PNI) is a clinical problem with high morbidity that can cause severe
damage. Surgical suturing or implants are usually required due to the slow speed and …