Aryl hydrocarbon receptor (AhR) is a member of the basic helix–loop–helix–(bHLH)
superfamily of transcription factors, which are associated with cellular responses to …

The aryl hydrocarbon receptor (AhR) is a cytoplasmic receptor and transcription factor
activated through cognate ligand binding. It is an important factor in immunity and tissue …

The induction of expression of genes for xenobiotic metabolizing enzymes in response to
chemical insult is an adaptive response found in most organisms. In vertebrates, the AhR is …

Traditionally considered as a critical intermediate in the toxic and carcinogenic response to
dioxin (2, 3, 7, 8-tetrachlorodibenzo-p-dioxin, TCDD), the Aryl hydrocarbon/Dioxin receptor …

Flavonoids, including isoflavones, are natural components in our diet and, with the
burgeoning interest in alternative medicine, are increasingly being ingested by the general …

Rutin is a citrus flavonoid glycoside, which is a low molecular weight polyphenolic
compound. There are various physiological functions of rutin and related flavonoids in the …

Flavonoids represent a group of phytochemicals exhibiting a wide range of biological
activities arising mainly from their antioxidant properties and ability to modulate several …

Flavonoids are present in fruits, vegetables and beverages derived from plants (tea, red
wine), and in many dietary supplements or herbal remedies including Ginkgo Biloba, Soy …

This chapter is an update of the data on substrates, reactions, inducers, and inhibitors of
human CYP enzymes published previously by Rendic and DiCarlo Citation 1a, Citation 1b …

CYP1A1 is one of the main cytochrome P450 enzymes, examined extensively for its capacity
to activate compounds with carcinogenic properties. Continuous exposure to inhalation …