Critical assessment of methods of protein structure prediction (CASP)—Round XIII

A Kryshtafovych, T Schwede, M Topf… - Proteins: Structure …, 2019 - Wiley Online Library
CASP (critical assessment of structure prediction) assesses the state of the art in modeling
protein structure from amino acid sequence. The most recent experiment (CASP13 held in …

[HTML][HTML] Designing a multi-epitope vaccine candidate to combat MERS-CoV by employing an immunoinformatics approach

S Mahmud, MO Rafi, GK Paul, MM Promi… - Scientific Reports, 2021 - nature.com
Currently, no approved vaccine is available against the Middle East respiratory syndrome
coronavirus (MERS-CoV), which causes severe respiratory disease. The spike glycoprotein …

Design of a multi-epitope-based vaccine targeting M-protein of SARS-CoV2: an immunoinformatics approach

VS Ayyagari, V TC, AP K, K Srirama - Journal of biomolecular …, 2022 - Taylor & Francis
In the present study, one of the targets present on the envelopes of coronaviruses,
membrane glycoprotein (M) was chosen for the design of a multi-epitope vaccine by …

CDC20 assists its catalytic incorporation in the mitotic checkpoint complex

V Piano, A Alex, P Stege, S Maffini, GA Stoppiello… - Science, 2021 - science.org
Open (O) and closed (C) topologies of HORMA-domain proteins are respectively associated
with inactive and active states of fundamental cellular pathways. The HORMA protein O …

The potential of plant-derived secondary metabolites as novel drug candidates against Klebsiella pneumoniae: Molecular docking and simulation investigation

SR Mahapatra, J Dey, TK Raj, V Kumar… - South African Journal of …, 2022 - Elsevier
Klebsiella pneumoniae is an important multidrug-resistant pathogen affecting humans and a
major source for hospital infections associated with high morbidity and mortality due to …

Immunoinformatics and molecular docking studies reveal a novel Multi-Epitope peptide vaccine against pneumonia infection

SR Mahapatra, J Dey, T Kaur, R Sarangi, AA Bajoria… - Vaccine, 2021 - Elsevier
Pneumonia is a major endemic disease around the world, and an effective vaccine is the
need of the hour to fight against the disease. When there are no appropriate antiviral and …

[HTML][HTML] Cell Surface Fibroblast Activation Protein-2 (Fap2) of Fusobacterium nucleatum as a Vaccine Candidate for Therapeutic Intervention of Human Colorectal …

S Padma, R Patra, PS Sen Gupta, SK Panda, MK Rana… - Vaccines, 2023 - mdpi.com
Colorectal cancer (CRC) is one of the most common cancers and is the second-highest in
cancer-related deaths worldwide. The changes in gut homeostasis and microbial dysbiosis …

[HTML][HTML] Multi-epitope-based vaccine candidate for monkeypox: an in silico approach

SAH Abdi, A Ali, SF Sayed, Abutahir, A Ali, P Alam - Vaccines, 2022 - mdpi.com
Currently, there are limited treatment options available for the monkeypox disease. We used
a computational strategy to design a specific antigenic vaccine against pathogens. After …

Protein sequence‐to‐structure learning: Is this the end (‐to‐end revolution)?

E Laine, S Eismann, A Elofsson… - … Structure, Function, and …, 2021 - Wiley Online Library
The potential of deep learning has been recognized in the protein structure prediction
community for some time, and became indisputable after CASP13. In CASP14, deep …

[HTML][HTML] Designing a multi-epitope vaccine against Mycobacteroides abscessus by pangenome-reverse vaccinology

HA Dar, S Ismail, Y Waheed, S Ahmad, Z Jamil… - Scientific reports, 2021 - nature.com
Abstract Mycobacteroides abscessus (Previously Mycobacterium abscessus) is an emerging
microorganism of the newly defined genera Mycobacteroides that causes mainly skin and …