Nauclea officinalis: A Chinese medicinal herb with phytochemical, biological, and pharmacological effects

B Liu, Q Geng, Z Cao, L Li, P Lu, L Lin, L Yan, C Lu - Chinese medicine, 2022 - Springer
Abstract Nauclea officinalis (N. officinalis), a medicinal plant of the genus Nauclea in the
family Rubiaceae, is used in the treatment of fever, pneumonia, pharyngolaryngitis, and …

Anti-inflammatory effect of the six compounds isolated from Nauclea officinalis Pierrc ex Pitard, and molecular mechanism of strictosamide via suppressing the NF-κB …

DY Li, JQ Chen, JQ Ye, XT Zhai, J Song… - Journal of …, 2017 - Elsevier
Abstract Ethnopharmacological relevance Nauclea officinalis Pierrc ex Pitard. is a Chinese
medicinal herb that contains high level of alkaloids which is the most abundant and active …

Bioinspired transformations using strictosidine aglycones: divergent total syntheses of monoterpenoid indole alkaloids in the early stage of biosynthesis

J Sakamoto, H Ishikawa - Chemistry–A European Journal, 2022 - Wiley Online Library
A series of bioinspired transformations that are applied to convert strictosidine aglycones
into monoterpenoid indole alkaloids is reported. The highly reactive key intermediates …

Simultaneous determination of 11 alkaloids in rat plasma by LC-ESI-MS/MS and a pharmacokinetic study after oral administration of total alkaloids extracted from …

G Wang, H Wang, Z Lin, L Hou, JY Wang… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Nauclea officinalis, a widely used Li medicine, has been
used for the treatment of cold, fever, bronchitis, pneumonia, acute tonsillitis, and other …

An insight into recent updates on analytical techniques for bioactive alkaloids

A Saini, K Seni, PA Chawla, V Chawla… - Phytochemical …, 2024 - Wiley Online Library
Introduction Alkaloids represent a wide class of naturally existing nitrogen‐containing
organic compounds having diverse biological activities. They are primary bioactive …

Chromatographic fingerprints analysis and determination of seven components in Danmu preparations by HPLC–DAD/QTOF-MS

N Li, J Zhang, Y Zhang, Z Ma, J Liao, H Cao, M Wu - Chinese medicine, 2020 - Springer
Abstract Background Danmu preparations (Danmu Capsule and Danmu Syrup), which are
made from Nauclea officinalis stem extracts, have good clinical efficacy in acute tonsillitis …

New Antidiabetic and Free-Radical Scavenging Potential of Strictosamide in Sarcocephalus pobeguinii Ground Bark Extract via Effect-Directed Analysis

I Yüce, H Agnaniet, GE Morlock - Acs Omega, 2019 - ACS Publications
The active principle of most traditional medicines is not known, as for Sarcocephalus
pobeguinii Hua ex Pellegr. bark extract. It is used as an antidiabetic drug in Gabonese folk …

Qualitative and quantitative analysis of the constituents in DANMU preparations by UPLC–PDA–TOF-MS

F Zhu, J Chen, J Wang, R Yin, X Li… - Journal of …, 2014 - academic.oup.com
An ultra performance liquid chromatography coupled with photodiode array detector and
time-of-flight tandem mass spectrometry (UPLC–PDA–TOF-MS) method was developed for …

Collective Synthesis of Monoterpenoid Indole Alkaloids Using Bioinspired Strategies

H Ishikawa - New Tide of Natural Product Chemistry, 2023 - Springer
In recent years, collective total synthesis, in which natural products are synthesized
exhaustively from common intermediates, has attracted attention in academia and industry …

Mass Spectroscopy as an analytical tool to harness the production of secondary plant metabolites: The way forward for drug discovery

F Ahmad, H Nadeem - Gene, Drug, and Tissue Engineering, 2022 - Springer
The molecular map of diverse biological molecules linked with structure, function, signaling,
and regulation within a cell can be elucidated using an analytically demanding omic …