Shared signaling pathways and targeted therapy by natural bioactive compounds for obesity and type 2 diabetes

S Tian, H Zhao, H Song - Critical Reviews in Food Science and …, 2024 - Taylor & Francis
Epidemiological evidence showed that patients suffering from obesity and T2DM are
significantly at higher risk for chronic low-grade inflammation, oxidative stress, nonalcoholic …

[HTML][HTML] Molecular targets of exercise mimetics and their natural activators

YJ Jang, S Byun - BMB reports, 2021 - ncbi.nlm.nih.gov
Physical exercise can be effective in preventing or ameliorating various diseases, including
diabetes, cardiovascular diseases, neurodegenerative diseases, and cancer. However, not …

Hydrangenol, an active constituent of Hydrangea serrata (Thunb.) Ser., ameliorates colitis through suppression of macrophage-mediated inflammation in dextran …

S Kim, KS Chung, SY Jang, HS Han, SW Heo… - Food & Function, 2023 - pubs.rsc.org
Ulcerative colitis (UC) is a chronic disease of the colon characterized by mucosal damage
and relapsing gastrointestinal inflammation. Hydrangea serrata (Thunb.) Ser. and its …

Yellow leaf green tea modulates the AMPK/ACC/SREBP1c signaling pathway and gut microbiota in high‐fat diet‐induced mice to alleviate obesity

B Tian, Y Pan, X Zhou, Y Jiang, X Zhang… - Journal of the …, 2024 - Wiley Online Library
BACKGROUND Yellow leaf green tea (YLGT) is a new variety of Camellia sinensis (L.) O.
Ktze, which has yellow leaves and the unique qualities of 'three green through three yellow' …

Protective effect of hydrangenol on lipopolysaccharide-induced endotoxemia by suppressing intestinal inflammation

SY Jang, SY Kim, HA Song, H Kim, KS Chung… - International …, 2023 - Elsevier
Hydrangenol, a dihydroisocoumarin, isolated from the leaves of Hydrangea serrata,
possesses anti-inflammatory, anti-obesity, and anti-photoaging activities. In this study, we …

Flammulina velutipes mycorrhizae dietary fiber improves lipid metabolism disorders in obese mice through activating AMPK signaling pathway mediated by gut …

W Wang, S Yang, S Song, J Zhang, F Jia - Food Bioscience, 2021 - Elsevier
Mounting evidence shows that dietary fiber (DF) alleviates lipid metabolism disorders in
humans and animals by regulating the gut microbiota. However, its action mechanisms …

Standardized Ethanol Extract of Cassia mimosoides var. nomame Makino Ameliorates Obesity via Regulation of Adipogenesis and Lipogenesis in 3T3-L1 Cells and …

SW Heo, KS Chung, YS Yoon, SY Kim, HS Ahn… - Nutrients, 2023 - mdpi.com
Obesity is a major cause of conditions such as type 2 diabetes and non-alcoholic fatty liver
disease, posing a threat to public health worldwide. Here, we analyzed the anti-obesity …

Standardized Hydrangea serrata (Thunb.) Ser. Extract Ameliorates Obesity in db/db Mice

HS Han, KS Chung, YK Shin, SH Lee, KT Lee - Nutrients, 2021 - mdpi.com
We previously reported the potential anti-obesity effects of the water extract of Hydrangea
serrata (Thunb.) Ser. leaves (WHS) in high-fat diet-induced obese mice. As an extension of …

A Botanical Mixture Consisting of Inula japonica and Potentilla chinensis Relieves Obesity via the AMPK Signaling Pathway in 3T3-L1 Adipocytes and HFD-Fed …

SY Lee, KS Chung, SR Son, SY Lee, DS Jang, JK Lee… - Nutrients, 2022 - mdpi.com
Excessive lipid accumulation in white adipose tissue (WAT) is the major cause of obesity.
Herein, we investigated the anti-obesity effect and molecular mechanism of a botanical …

Anti-obesity effects of a standardized ethanol extract of Eisenia bicyclis by regulating the AMPK signaling pathway in 3T3-L1 cells and HFD-induced mice

YS Yoon, KS Chung, SY Lee, SW Heo, YR Kim… - Food & Function, 2024 - pubs.rsc.org
Obesity requires treatment to mitigate the potential development of further metabolic
disorders, including diabetes, hyperlipidemia, tumor growth, and non-alcoholic fatty liver …