Ferroptosis is recognized as a new form of regulated cell death which is initiated by severe
lipid peroxidation relying on reactive oxygen species (ROS) generation and iron overload …

The COVID-19 pandemic caused by the coronavirus (SARS-CoV-2) has taken the world by
surprise into a major crisis of overwhelming morbidity and mortality. This highly infectious …

Background and Aims NAFLD and its more‐advanced form, steatohepatitis (NASH), is
associated with obesity and is an independent risk factor for cardiovascular, liver‐related …

In animals, mitochondria are mainly organised into an interconnected tubular network
extending across the cell along a cytoskeletal scaffold. Mitochondrial fission and fusion, as …

Adiponectin (a protein consisting of 244 amino acids and characterized by a molecular
weight of 28 kDa) is a cytokine that is secreted from adipose tissues (adipokine). Available …

Oxidative stress-induced damage to the retinal pigment epithelium (RPE) is considered to
be a key factor in age-related macular degeneration (AMD) pathology. RPE cells are …

Lipid mobilization through fatty acid β-oxidation is a central process essential for energy
production during nutrient shortage. In yeast, this catabolic process starts in the peroxisome …

With the growing prevalence of cardiovascular disease (CVD), there is an urgent need to
explore non-conventional therapeutic measures to alleviate the burden of CVD on global …

In the present study, we hypothesized that hypoxia-inducible factor 1α (HIF-1α)-mediated
mitophagy plays a protective role in ischemia/reperfusion (I/R)-induced acute kidney injury …

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease
worldwide, and scientific studies consistently report that NAFLD development can be …