Potassium channels are widely distributed integral proteins responsible for the effective and
selective transport of K+ ions through the biological membranes. According to the existing …

Covering: 1996–December 2016 The human Ether-à-go-go Related Gene (hERG) channel
is a voltage-gated potassium channel playing an essential role in the normal electrical …

This chapter presents a synopsis of African medicinal plants and their derived products with
antimycobacterial properties. Several secondary plant metabolites are reported to have anti …

Multiple plant species are used in traditional southern African medicine to treat
cardiovascular diseases. Traditional southern African therapies used to treat cardiovascular …

Background Embelin is a hydroxybenzoquinone constituent of the Embelia species that has
anti-disease properties. However, its toxicity, particularly the in silico, acute, and …

Human ether-a-go-go-related gene channel blocking is associated with QT interval
prolongation and increased risk of potentially fatal arrhythmias. As natural products keep …

The cardiac action potential is regulated by several ion channels. Drugs capable to block
these channels, in particular the human ether-à-go-go-related gene (hERG) channel, also …

Abstract Casimiroa edulis La Llave is known to contain unusual 5, 6-dimethoxyflavones
bearing a variously oxygenated B-ring. Phytochemical investigation of the leaves and the …

Breast cancer is the second most commonly diagnosed cancer and the leading cause of
cancer deaths in women. Several factors, such as the costs of anti-cancer drugs, drug …

The human Ether-a-go-go Related Gene (hERG) channel is a voltage-gated potassium
channel playing an essential role in the normal electrical activity in the heart. It is involved in …