Haemozoin formation
TJ Egan - Molecular and biochemical parasitology, 2008 - Elsevier
Formation of malaria pigment or haemozoin is the major route of haem detoxification in the
malaria parasite Plasmodium falciparum as well as several other species of …
malaria parasite Plasmodium falciparum as well as several other species of …
Heme and blood-feeding parasites: friends or foes?
Hemoparasites, like malaria and schistosomes, are constantly faced with the challenges of
storing and detoxifying large quantities of heme, released from their catabolism of host …
storing and detoxifying large quantities of heme, released from their catabolism of host …
Probing the biophysical interplay between a viral genome and its capsid
J Snijder, C Uetrecht, RJ Rose, R Sanchez-Eugenia… - Nature …, 2013 - nature.com
The interaction between a viral capsid and its genome governs crucial steps in the life cycle
of a virus, such as assembly and genome uncoating. Tuning cargo–capsid interactions is …
of a virus, such as assembly and genome uncoating. Tuning cargo–capsid interactions is …
Ironing out the details: exploring the role of iron and heme in blood-sucking arthropods
SR Whiten, H Eggleston, ZN Adelman - Frontiers in Physiology, 2018 - frontiersin.org
Heme and iron are essential molecules for many physiological processes and yet have the
ability to cause oxidative damage such as lipid peroxidation, protein degradation, and …
ability to cause oxidative damage such as lipid peroxidation, protein degradation, and …
Iron metabolism in hard ticks (Acari: Ixodidae): the antidote to their toxic diet
RL Galay, R Umemiya-Shirafuji, M Mochizuki… - Parasitology …, 2015 - Elsevier
Ticks are notorious parasitic arthropods, known for their completely host-blood-dependent
lifestyle. Hard ticks (Acari: Ixodidae) feed on their hosts for several days and can ingest …
lifestyle. Hard ticks (Acari: Ixodidae) feed on their hosts for several days and can ingest …
Heme-induced ROS in Trypanosoma cruzi activates CaMKII-like that triggers epimastigote proliferation. One helpful effect of ROS
NPA Nogueira, CF Souza, FMS Saraiva, PE Sultano… - PloS one, 2011 - journals.plos.org
Heme is a ubiquitous molecule that has a number of physiological roles. The toxic effects of
this molecule have been demonstrated in various models, based on both its pro-oxidant …
this molecule have been demonstrated in various models, based on both its pro-oxidant …
Application of principal component analysis to multispectral-multimodal optical image analysis for malaria diagnostics
Background Multispectral imaging microscopy is a novel microscopic technique that
integrates spectroscopy with optical imaging to record both spectral and spatial information …
integrates spectroscopy with optical imaging to record both spectral and spatial information …
[HTML][HTML] Extracellular lipid droplets promote hemozoin crystallization in the gut of the blood fluke Schistosoma mansoni
JBRC Soares, CM Maya-Monteiro… - FEBS letters, 2007 - Elsevier
Hemozoin (Hz) is a heme crystal produced upon hemoglobin digestion as the main
mechanism of heme disposal in several hematophagous organisms. Here, we show that, in …
mechanism of heme disposal in several hematophagous organisms. Here, we show that, in …
Peritrophic matrices
H Merzendorfer, M Kelkenberg… - … composite matrices in …, 2016 - Springer
The peritrophic matrix (PM) is an invertebrate intestinal lining, which partitions the midgut
lumen into separate digestive compartments, lubricates the lumenal surface to protect from …
lumen into separate digestive compartments, lubricates the lumenal surface to protect from …
Increase on the Initial Soluble Heme Levels in Acidic Conditions Is an Important Mechanism for Spontaneous Heme Crystallization In Vitro
Background Hemozoin (Hz) is a heme crystal that represents a vital pathway for heme
disposal in several blood-feeding organisms. Recent evidence demonstrated that β-hematin …
disposal in several blood-feeding organisms. Recent evidence demonstrated that β-hematin …