Native mass spectrometry: recent progress and remaining challenges
Native mass spectrometry (nMS) has emerged as an important tool in studying the structure
and function of macromolecules and their complexes in the gas phase. In this review, we …
and function of macromolecules and their complexes in the gas phase. In this review, we …
Native mass spectrometry of membrane proteins
Biological membranes formed of amphipathic lipid bilayers provide chemical barriers to
separate cells from their external environments and define subcellular compartments …
separate cells from their external environments and define subcellular compartments …
Approaches to heterogeneity in native mass spectrometry
AD Rolland, JS Prell - Chemical reviews, 2021 - ACS Publications
Native mass spectrometry (MS) is aimed at preserving and determining the native structure,
composition, and stoichiometry of biomolecules and their complexes from solution after they …
composition, and stoichiometry of biomolecules and their complexes from solution after they …
Variable-temperature electrospray ionization for temperature-dependent folding/refolding reactions of proteins and ligand binding
Stabilities and structure (s) of proteins are directly coupled to their local environment or
Gibbs free energy landscape as defined by solvent, temperature, pressure, and …
Gibbs free energy landscape as defined by solvent, temperature, pressure, and …
Fourier transform-ion mobility-orbitrap mass spectrometer: a next-generation instrument for native mass spectrometry
ML Poltash, JW McCabe, M Shirzadeh… - Analytical …, 2018 - ACS Publications
A new instrument configuration for native ion mobility-mass spectrometry (IM-MS) is
described. Macromolecule ions are generated by using a static ESI source coupled to an RF …
described. Macromolecule ions are generated by using a static ESI source coupled to an RF …
First-principles collision cross section measurements of large proteins and protein complexes
JW McCabe, CS Mallis, KI Kocurek… - Analytical …, 2020 - ACS Publications
Rotationally averaged collision cross section (CCS) values for a series of proteins and
protein complexes ranging in size from 8.6 to 810 kDa are reported. The CCSs were …
protein complexes ranging in size from 8.6 to 810 kDa are reported. The CCSs were …
[HTML][HTML] Interpol review of detection and characterization of explosives and explosives residues 2016-2019
DJ Klapec, G Czarnopys, J Pannuto - Forensic science international …, 2020 - Elsevier
This review paper covers the forensic-relevant literature for the analysis and detection of
explosives and explosives residues from 2016-2019 as a part of the 19 th Interpol …
explosives and explosives residues from 2016-2019 as a part of the 19 th Interpol …
Selective regulation of human TRAAK channels by biologically active phospholipids
S Schrecke, Y Zhu, JW McCabe, M Bartz… - Nature chemical …, 2021 - nature.com
TRAAK is an ion channel from the two-pore domain potassium (K2P) channel family with
roles in maintaining the resting membrane potential and fast action potential conduction …
roles in maintaining the resting membrane potential and fast action potential conduction …
Cardiolipin regulates the activity of the mitochondrial ABC transporter ABCB10
T Zhang, J Lyu, Y Zhu, A Laganowsky - Biochemistry, 2023 - ACS Publications
The ATP-binding cassette (ABC) transporter ABCB10 resides in the inner membrane of
mitochondria and is implicated in erythropoiesis. Mitochondria from different cell types share …
mitochondria and is implicated in erythropoiesis. Mitochondria from different cell types share …
Implementing Digital-Waveform Technology for Extended m/z Range Operation on a Native Dual-Quadrupole FT-IM-Orbitrap Mass Spectrometer
Here, we describe a digital-waveform dual-quadrupole mass spectrometer that enhances
the performance of our drift tube FT-IMS high-resolution Orbitrap mass spectrometer (MS) …
the performance of our drift tube FT-IMS high-resolution Orbitrap mass spectrometer (MS) …