[HTML][HTML] Molecular pathways involved in COVID-19 and potential pathway-based therapeutic targets
M Farahani, Z Niknam, LM Amirabad… - Biomedicine & …, 2022 - Elsevier
Deciphering the molecular downstream consequences of severe acute respiratory
syndrome coronavirus (SARS-CoV)− 2 infection is important for a greater understanding of …
syndrome coronavirus (SARS-CoV)− 2 infection is important for a greater understanding of …
The miRNA: a small but powerful RNA for COVID-19
Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) is a severe and rapidly evolving epidemic. Now …
syndrome coronavirus 2 (SARS-CoV-2) is a severe and rapidly evolving epidemic. Now …
[HTML][HTML] HIF-1α promotes SARS-CoV-2 infection and aggravates inflammatory responses to COVID-19
M Tian, W Liu, X Li, P Zhao, MA Shereen… - … and Targeted Therapy, 2021 - nature.com
Cytokine storm induced by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-
2) is a major pathological feature of Coronavirus Disease 2019 (COVID-19) and a crucial …
2) is a major pathological feature of Coronavirus Disease 2019 (COVID-19) and a crucial …
Network pharmacology and molecular docking analyses on Lianhua Qingwen capsule indicate Akt1 is a potential target to treat and prevent COVID‐19
Abstract Objectives Coronavirus disease 2019 (COVID‐19) is rapidly spreading worldwide.
Lianhua Qingwen capsule (LQC) has shown therapeutic effects in patients with COVID‐19 …
Lianhua Qingwen capsule (LQC) has shown therapeutic effects in patients with COVID‐19 …
The PI3K/Akt/mTOR pathway: A potential pharmacological target in COVID-19
MS Basile, E Cavalli, J McCubrey… - Drug discovery today, 2022 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) has emerged as a serious threat to global
health. The disregulation of the phosphatidylinositol 3-kinase/protein kinase B/mammalian …
health. The disregulation of the phosphatidylinositol 3-kinase/protein kinase B/mammalian …
[HTML][HTML] Potential therapeutic targets and vaccine development for SARS-CoV-2/COVID-19 pandemic management: a review on the recent update
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a highly pathogenic
novel virus that has caused a massive pandemic called coronavirus disease 2019 (COVID …
novel virus that has caused a massive pandemic called coronavirus disease 2019 (COVID …
[HTML][HTML] Imatinib and methazolamide ameliorate COVID-19-induced metabolic complications via elevating ACE2 enzymatic activity and inhibiting viral entry
Z Li, M Peng, P Chen, C Liu, A Hu, Y Zhang, J Peng… - Cell Metabolism, 2022 - cell.com
Summary Coronavirus disease 2019 (COVID-19) represents a systemic disease that may
cause severe metabolic complications in multiple tissues including liver, kidney, and …
cause severe metabolic complications in multiple tissues including liver, kidney, and …
[HTML][HTML] Metabolic perturbation associated with COVID-19 disease severity and SARS-CoV-2 replication
S Krishnan, H Nordqvist, AT Ambikan, S Gupta… - Molecular & Cellular …, 2021 - ASBMB
Viruses hijack host metabolic pathways for their replicative advantage. In this study, using
patient-derived multiomics data and in vitro infection assays, we aimed to understand the …
patient-derived multiomics data and in vitro infection assays, we aimed to understand the …
[HTML][HTML] Complement activation in COVID-19 and targeted therapeutic options: a scoping review
EHT Lim, RBE van Amstel, VV de Boer, LA van Vught… - Blood Reviews, 2023 - Elsevier
Increasing evidence suggests that activation of the complement system plays a key role in
the pathogenesis and disease severity of Coronavirus disease 2019 (COVID-19). We used a …
the pathogenesis and disease severity of Coronavirus disease 2019 (COVID-19). We used a …
[HTML][HTML] Data, reagents, assays and merits of proteomics for SARS-CoV-2 research and testing
As the COVID-19 pandemic continues to spread, thousands of scientists around the globe
have changed research direction to understand better how the virus works and to find out …
have changed research direction to understand better how the virus works and to find out …