Recent advances in neuropeptide signaling in Drosophila, from genes to physiology and behavior

DR Nässel, M Zandawala - Progress in neurobiology, 2019 - Elsevier
This review focuses on neuropeptides and peptide hormones, the largest and most diverse
class of neuroactive substances, known in Drosophila and other animals to play roles in …

Marine peptides: Bioactivities and applications

RCF Cheung, TB Ng, JH Wong - Marine drugs, 2015 - mdpi.com
Peptides are important bioactive natural products which are present in many marine
species. These marine peptides have high potential nutraceutical and medicinal values …

[HTML][HTML] System-wide mapping of peptide-GPCR interactions in C. elegans

I Beets, S Zels, E Vandewyer, J Demeulemeester… - Cell reports, 2023 - cell.com
Neuropeptides and peptide hormones are ancient, widespread signaling molecules that
underpin almost all brain functions. They constitute a broad ligand-receptor network, mainly …

Evolution of neuropeptide signalling systems

MR Elphick, O Mirabeau… - Journal of Experimental …, 2018 - journals.biologists.com
Neuropeptides are a diverse class of neuronal signalling molecules that regulate
physiological processes and behaviour in animals. However, determining the relationships …

The chemical brain hypothesis for the origin of nervous systems

G Jékely - … Transactions of the Royal Society B, 2021 - royalsocietypublishing.org
In nervous systems, there are two main modes of transmission for the propagation of activity
between cells. Synaptic transmission relies on close contact at chemical or electrical …

Tachykinins: neuropeptides that are ancient, diverse, widespread and functionally pleiotropic

DR Nässel, M Zandawala, T Kawada… - Frontiers in …, 2019 - frontiersin.org
Tachykinins (TKs) are ancient neuropeptides present throughout the bilaterians and are,
with some exceptions, characterized by a conserved FX1GX2Ramide carboxy terminus …

Single-cell atlases of two lophotrochozoan larvae highlight their complex evolutionary histories

L Piovani, DJ Leite, LA Yañez Guerra, F Simpson… - Science …, 2023 - science.org
Pelagic larval stages are widespread across animals, yet it is unclear whether larvae were
present in the last common ancestor of animals or whether they evolved multiple times due …

Transcriptomic identification of starfish neuropeptide precursors yields new insights into neuropeptide evolution

DC Semmens, O Mirabeau, I Moghul… - Open …, 2016 - royalsocietypublishing.org
Neuropeptides are evolutionarily ancient mediators of neuronal signalling in nervous
systems. With recent advances in genomics/transcriptomics, an increasingly wide range of …

Regulation of feeding and metabolism by neuropeptide F and short neuropeptide F in invertebrates

M Fadda, I Hasakiogullari, L Temmerman… - Frontiers in …, 2019 - frontiersin.org
Numerous neuropeptide systems have been implicated to coordinately control energy
homeostasis, both centrally and peripherally. However, the vertebrate neuropeptide Y (NPY) …

Large-scale combinatorial deorphanization of Platynereis neuropeptide GPCRs

P Bauknecht, G Jékely - Cell reports, 2015 - cell.com
Neuropeptides, representing the largest class of neuromodulators, commonly signal by G-
protein-coupled receptors (GPCRs). While the neuropeptide repertoire of several metazoans …