Lipids in the nervous system accomplish a great number of key functions, from
synaptogenesis to impulse conduction, and more. Most of the lipids of the nervous system …

Multiple sclerosis (MS) is characterized by chronic inflammatory response-induced
demyelination of the neurons and degeneration of the axons within the central nervous …

The immune response of the CNS is a defense mechanism activated upon injury to initiate
repair mechanisms while chronic over-activation of the CNS immune system (termed …

Pelizaeus–Merzbacher disease (PMD) is an untreatable and fatal leukodystrophy. In a
model of PMD with perturbed blood–brain barrier integrity, cholesterol supplementation …

Multiple sclerosis (MS) is an immune-mediated chronic inflammatory demyelinating disease
of the central nervous system (CNS). The aim of the current study was to investigate the …

Background Multiple sclerosis (MS), a chronic auto-immune, inflammatory, and
degenerative disease of the central nervous system, affects both males and females; …

Age-related muscle weakness and loss of muscle mass (sarcopenia) is a universal problem
in the elderly. Our previous studies indicate that alpha motor neurons (α-MNs) play a critical …

Lipids are apolar small molecules known not only as components of cell membranes but
also, in recent literature, as modulators of different biological functions. Herein, we focused …

This review focuses on the roles of glia and polyamines (PAs) in brain function and
dysfunction, highlighting how PAs are one of the principal differences between glia and …

Multiple sclerosis is characterized by inflammatory processes occurring within the central
nervous system. In multiple sclerosis, inflammation could be either a physiological response …