Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review
P Csermely, T Korcsmáros, HJM Kiss, G London… - Pharmacology & …, 2013 - Elsevier
Despite considerable progress in genome-and proteome-based high-throughput screening
methods and in rational drug design, the increase in approved drugs in the past decade did …
methods and in rational drug design, the increase in approved drugs in the past decade did …
[HTML][HTML] A neural network multi-task learning approach to biomedical named entity recognition
Abstract Background Named Entity Recognition (NER) is a key task in biomedical text
mining. Accurate NER systems require task-specific, manually-annotated datasets, which …
mining. Accurate NER systems require task-specific, manually-annotated datasets, which …
[HTML][HTML] Genomic clustering within functionally related gene families in Ascomycota fungi
D Hagee, AA Hardan, J Botero, JT Arnone - Computational and Structural …, 2020 - Elsevier
Multiple mechanisms collaborate for proper regulation of gene expression. One layer of this
regulation is through the clustering of functionally related genes at discrete loci throughout …
regulation is through the clustering of functionally related genes at discrete loci throughout …
[HTML][HTML] Identification of research hypotheses and new knowledge from scientific literature
Background Text mining (TM) methods have been used extensively to extract relations and
events from the literature. In addition, TM techniques have been used to extract various …
events from the literature. In addition, TM techniques have been used to extract various …
Cis-acting variation is common across regulatory layers but is often buffered during embryonic development
Precise patterns of gene expression are driven by interactions between transcription factors,
regulatory DNA sequences, and chromatin. How DNA mutations affecting any one of these …
regulatory DNA sequences, and chromatin. How DNA mutations affecting any one of these …
Stochastic representation of FGM copulas using multivariate Bernoulli random variables
C Blier-Wong, H Cossette, E Marceau - Computational Statistics & Data …, 2022 - Elsevier
A one-to-one correspondence between Fréchet's class of multivariate Bernoulli distribution
with symmetric marginals and the well-known family of Farlie-Gumbel-Morgenstern (FGM) …
with symmetric marginals and the well-known family of Farlie-Gumbel-Morgenstern (FGM) …
Copulas and their potential for ecology
All branches of ecology study relationships among and between environmental and
biological variables. However, standard approaches to studying such relationships, based …
biological variables. However, standard approaches to studying such relationships, based …
Analysis of directional dependence using asymmetric copula-based regression models
D Kim, JM Kim - Journal of Statistical Computation and Simulation, 2014 - Taylor & Francis
The directional dependence between variables using asymmetric copula regression has
drawn much attention in recent years. There are, however, some critical issues which have …
drawn much attention in recent years. There are, however, some critical issues which have …
A new approach to interspecific synchrony in population ecology using tail association
S Ghosh, LW Sheppard, PC Reid… - Ecology and …, 2020 - Wiley Online Library
Standard methods for studying the association between two ecologically important variables
provide only a small slice of the information content of the association, but statistical …
provide only a small slice of the information content of the association, but statistical …
On the copula correlation ratio and its generalization
JH Shih, T Emura - Journal of Multivariate Analysis, 2021 - Elsevier
The correlation ratio has been used to measure how much the behavior of one variable can
be predicted by the other variable. In this paper, we derive a new expression of the …
be predicted by the other variable. In this paper, we derive a new expression of the …