The aim is to elucidate the relationship between sickle cell disorder and severe COVID‐19.
We systematically searched the required articles in three electronic databases, extracting …

Sickle cell disease (SCD) is one of the commonest severe inherited disorders, but specific
treatments are lacking and the pathophysiology remains unclear. Affected individuals …

Cell dehydration is a distinguishing characteristic of sickle cell disease and an important
contributor to disease pathophysiology. Due to the unique dependence of Hb S …

Haemoglobin (Hb) SC disease is the second most common subtype of sickle cell disease
and is potentially fatal. This study aimed to determine the clinical characteristics, outcome …

Background To describe the characteristics of dengue in sickle cell children and try to
identify risk factors of severity. Methods In this retrospective study, we describe the evolution …

Key points• The high cation permeability in red blood cells (RBCs) from patients with sickle
cell disease (SCD) is central to pathogenesis and includes a deoxygenation‐induced …

Objectives: Hemoglobin SC is the second most common variant of sickle-cell disease
worldwide, after hemoglobin SS. The objectives of the study were to describe the clinical …

Phosphatidylserine (PS) exposure in red blood cells (RBCs) from sickle cell disease (SCD)
patients is increased compared to levels in normal individuals and may participate in the …

HbSC disease is the second commonest form of sickle cell disease, with poorly understood
pathophysiology and few treatments. We studied the role of K-Cl cotransport activity in …

This study aimed to determine the effect of haemolysis on plasma oxidation and nitration in
sickle cell disease (SCD) patients. Blood was collected from haemoglobin (Hb) A volunteers …