Natural products as anthelmintics: safeguarding animal health

AA Salim, MS Butler, MAT Blaskovich… - Natural Product …, 2023 - pubs.rsc.org
Covering literature to December 2022 This review provides a comprehensive account of all
natural products (500 compounds, including 17 semi-synthetic derivatives) described in the …

Moringa oleifera as a Natural Alternative for the Control of Gastrointestinal Parasites in Equines: A Review

MMMY Elghandour, A Maggiolino… - Plants, 2023 - mdpi.com
Studies have shown a wide variety of parasites that infect horses, causing major
gastrointestinal damage that can lead to death, and although the main method of control has …

[HTML][HTML] Synthesis and anthelmintic activity of novel thiosemicarbazide and 1, 2, 4-triazole derivatives: in vitro, in vivo, and in silico study

P Kołodziej, M Wujec, M Doligalska… - Journal of Advanced …, 2024 - Elsevier
Introduction Intestinal parasitic infections are neglected diseases and, due to the increasing
resistance of parasites to available drugs, they pose an increasing therapeutic challenge …

An overview of anthelmintic resistance in domestic ruminants in Brazil

LO Macedo, SS Silva, LC Alves, GA Carvalho… - Ruminants, 2023 - mdpi.com
Gastrointestinal nematodes (GIN) significantly, negatively impact livestock worldwide, and
their control depends on the use of chemotherapy drugs. However, this approach is …

Phenolic Acids and Flavonoids from Pithecellobium dulce (Robx.) Benth Leaves Exhibit Ovicidal Activity against Haemonchus contortus

A Olmedo-Juárez, AL Jimenez-Chino, A Bugarin… - Plants, 2022 - mdpi.com
Pithecellobium dulce (Robx.) Benth is an arboreal legume used in traditional medicine for
the treatment of several ailments, including a number of intestinal disorders, and as a natural …

Anthelmintic activity of European fern extracts against Haemonchus contortus

A Pavičić, M Zajíčková, M Šadibolová, G Svobodová… - Veterinary …, 2023 - Springer
Most drugs used in the treatment of helminthiasis in humans and animals have lost their
efficacy due to the development of drug-resistance in helminths. Moreover, since …

Analytic Approaches in Genomic Epidemiological Studies of Parasitic Protozoa

T Wang, Z Zhang, Y Feng, L Xiao - … and Emerging Diseases, 2024 - Wiley Online Library
Whole genome sequencing (WGS) plays an important role in the advanced characterization
of pathogen transmission and is widely used in studies of major bacterial and viral diseases …

[HTML][HTML] Exploring the Interactions between Plant Proanthocyanidins and Thiabendazole: Insights from Isothermal Titration Calorimetry

M Sillanpää, MT Engström, P Tähtinen, RJ Green… - Molecules, 2024 - mdpi.com
Anthelmintic resistance in gastrointestinal nematodes produces substantial challenges to
agriculture, and new strategies for nematode control in livestock animals are called for …

Transcriptomics of ivermectin response in Caenorhabditis elegans: Integrating abamectin quantitative trait loci and comparison to the Ivermectin-exposed DA1316 …

F Dube, A Hinas, N Delhomme, M Åbrink, S Svärd… - Plos one, 2023 - journals.plos.org
Parasitic nematodes pose a significant threat to human and animal health, as well as cause
economic losses in the agricultural sector. The use of anthelmintic drugs, such as Ivermectin …

Flubendazole carbonyl reduction in drug-susceptible and drug-resistant strains of the parasitic nematode Haemonchus contortus: changes during the life cycle and …

N Rychlá, M Navrátilová, E Kohoutová… - Veterinary …, 2024 - Springer
Carbonyl-reducing enzymes (CREs) catalyse the reduction of carbonyl groups in many
eobiotic and xenobiotic compounds in all organisms, including helminths. Previous studies …