Obesity is a major global health problem determined by heredity and environment, and its
incidence is increasing yearly. In recent years, increasing evidence linking obesity to the gut …

Health is usually defined as the absence of pathology. Here, we endeavor to define health
as a compendium of organizational and dynamic features that maintain physiology. The …

Gut microbiota includes a vast collection of microorganisms residing within the
gastrointestinal tract. It is broadly recognized that the gut and brain are in constant …

Gut microbiota dysbiosis has been repeatedly observed in obesity and type 2 diabetes
mellitus, two metabolic diseases strongly intertwined with non-alcoholic fatty liver disease …

I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …

Conceptual scientific and medical advances have led to a recent realization that there may
be no single, one-size-fits-all diet and that differential human responses to dietary inputs …

The metabolic syndrome (MetS) is a constellation of risk factors that, if left untreated, will
often progress to greater metabolic defects such as type 2 diabetes and nonalcoholic fatty …

Since the renaissance of microbiome research in the past decade, much insight has
accumulated in comprehending forces shaping the architecture and functionality of resident …

Ageing and age-related diseases share some basic mechanistic pillars that largely
converge on inflammation. During ageing, chronic, sterile, low-grade inflammation—called …

Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …