Overweight and obesity are the result of a chronic positive energy balance, and therefore the
only effective therapies are a diet which, on the long term, provides lower calories than the …

The hypothalamo–pituitary–adrenal (HPA) axis is the critical mediator of the vertebrate
stress response system, responding to environmental stressors by maintaining internal …

Neuropeptide Y (NPY) and cocaine and amphetamine regulated transcript (CART) are two
neuropeptides involved in the regulation of feeding in both mammals and fish. NPY …

In mammals, circadian rhythms of physiology and behavior are regulated by a complex
network of cellular molecular oscillators distributed throughout the brain and peripheral …

CART is expressed abundantly in the hypothalamic paraventricular nucleus and locus
coeruleus, major corticotropin releasing factor (CRF) and noradrenaline sources …

Endocannabinoids acting at CB1 cannabinoid receptors (CB1) increase appetite. In view of
the predominant presynaptic localization of CB1 in the brain, we tested the hypothesis that …

Cocaine-and amphetamine-related transcript (CART) is a neuropeptide first discovered in
the striatum of the rat brain. Later, the genetic sequence and function of CART peptide …

Cocaine-and amphetamine-regulated transcript peptide (CART) with its wide distribution in
the brain of mammals has been the focus of considerable research in recent years. Last two …

In mammals the suprachiasmatic nucleus (SCN), the master circadian clock, is sensitive to
light input via the optic chiasm and synchronizes many daily biological rhythms. Here we …

The g-protein coupled receptor GPR-160, recently identified as a putative receptor for the
cocaine and amphetamine-regulated transcript (CART) peptide, shows abundant …