Nucleic acid-guided nucleases

RT Gill, A Garst, TEW Lipscomb - US Patent 9,982,279, 2018 - Google Patents
2017-08-22 Assigned to MUSE BIOTECHNOLOGY, INC. reassignment MUSE
BIOTECHNOLOGY, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …

Methods for generating barcoded combinatorial libraries

RT Gill, A Garst, TEW Lipscomb, MC Bassalo… - US Patent …, 2018 - Google Patents
2018-02-08 Assigned to THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY
CORPORATE reassignment THE REGENTS OF THE UNIVERSITY OF COLORADO, A …

Using truncated guide RNAs (tru-gRNAs) to increase specificity for RNA-guided genome editing

JK Joung, JD Sander, M Maeder, Y Fu - US Patent 9,567,604, 2017 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
51537665&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

CRISPR enabled multiplexed genome engineering

RT Gill, A Garst - US Patent 10,266,849, 2019 - Google Patents
US10266849B2 - CRISPR enabled multiplexed genome engineering - Google Patents
US10266849B2 - CRISPR enabled multiplexed genome engineering - Google Patents CRISPR …

Using RNA-guided FokI nucleases (RFNs) to increase specificity for RNA-guided genome editing

JK Joung, S Tsai - US Patent 9,567,603, 2017 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
51537665&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Increasing specificity for RNA-guided genome editing

JK Joung, J Angstman, JD Sander, M Maeder… - US Patent …, 2018 - Google Patents
US9885033B2 - Increasing specificity for RNA-guided genome editing - Google Patents
US9885033B2 - Increasing specificity for RNA-guided genome editing - Google Patents …

RNA-guided targeting of genetic and epigenomic regulatory proteins to specific genomic loci

JK Joung, M Maeder - US Patent 10,760,064, 2020 - Google Patents
BACKGROUND Clustered Regulatory Interspaced Short Palindromic Repeats (CRISPR),
and CRISPR-associated (cas) genes, referred to as CRISPR/Cas systems, are used by …

Using truncated guide RNAs (tru-gRNAs) to increase specificity for RNA-guided genome editing

JK Joung, JD Sander, Y Fu, M Maeder - US Patent 10,119,133, 2018 - Google Patents
CRISPR-Cas genome editing uses a guide RNA, which includes both a complementarity
region, which binds the target DNA by base-pairing, and a Cas9-binding region, to direct a …

Methods for generating barcoded combinatorial libraries

RT Gill, A Garst, TEW Lipscomb, MC Bassalo… - US Patent …, 2019 - Google Patents
2018-05-22 Assigned to THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY
CORPORATE reassignment THE REGENTS OF THE UNIVERSITY OF COLORADO, A …

Nucleic acid-guided nucleases

RT Gill, A Garst, TEW Lipscomb - US Patent 10,011,849, 2018 - Google Patents
2017-08-22 Assigned to MUSE BIOTECHNOLOGY, INC. reassignment MUSE
BIOTECHNOLOGY, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …