Ageing and chronic degenerative pathologies demonstrate the shared characteristics of
high bioavailability of reactive oxygen species (ROS) and oxidative stress, chronic/persistent …

Osteoarthritis (OA) is a degenerative joint disorder commonly encountered in clinical
practice, and is the leading cause of disability in elderly people. Due to the poor self-healing …

Mesenchymal stem cells (MSCs), the major stem cells for cell therapy, have been used in
the clinic for approximately 10 years. From animal models to clinical trials, MSCs have …

Human mesenchymal stem cells (MSCs) are multilineage somatic progenitor/stem cells that
have been shown to possess immunomodulatory properties in recent years. Initially met with …

Diarthrodial joints are well suited to intra-articular injection, and the local delivery of
therapeutics in this fashion brings several potential advantages to the treatment of a wide …

Background Many patients report symptomatic relief after undergoing arthroscopy of the
knee for osteoarthritis, but it is unclear how the procedure achieves this result. We …

The concept of mesenchymal stem cells (MSCs) is becoming increasingly obscure due to
the recent findings of heterogeneous populations with different levels of stemness within …

Targeted cell delivery by a magnetically actuated microrobot with a porous structure is a
promising technique to enhance the low targeting efficiency of mesenchymal stem cell …

Mesenchymal stem cells (MSCs) have great potential for treating various diseases,
especially those related to tissue damage involving immune reactions. Various studies have …

Macroscale drug delivery (MDD) devices are engineered to exert spatiotemporal control
over the presentation of a wide range of bioactive agents, including small molecules …