[HTML][HTML] Caffeine-tolerant mutations selected through an at-home yeast experimental evolution teaching lab

NG Moresi, RC Geck, R Skophammer… - microPublication …, 2023 - ncbi.nlm.nih.gov
Abstract yEvo is a curriculum for high school students centered around evolution
experiments in S. cerevisiae. To adapt the curriculum for remote instruction, we created a …

Experimental evolution of Saccharomyces cerevisiae for caffeine tolerance alters multidrug resistance and target of rapamycin signaling pathways

RC Geck, NG Moresi, LM Anderson… - G3: Genes …, 2024 - academic.oup.com
Caffeine is a natural compound that inhibits the major cellular signaling regulator target of
rapamycin (TOR), leading to widespread effects including growth inhibition. Saccharomyces …

yEvo: experimental evolution in high school classrooms selects for novel mutations that impact clotrimazole resistance in Saccharomyces cerevisiae

MB Taylor, R Skophammer, AR Warwick, RC Geck… - G3, 2022 - academic.oup.com
Antifungal resistance in pathogenic fungi is a growing global health concern.
Nonpathogenic laboratory strains of Saccharomyces cerevisiae are an important model for …

[HTML][HTML] Experimental evolution of S. cerevisiae for caffeine tolerance alters multidrug resistance and TOR signaling pathways

RC Geck, NG Moresi, LM Anderson, R Brewer… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Caffeine is a natural compound that inhibits the major cellular signaling regulator TOR,
leading to widespread effects including growth inhibition. S. cerevisiae yeast can adapt to …

[PDF][PDF] Experimental evolution of Saccharomyces cerevisiae for caffeine tolerance alters multidrug resistance and target of rapamycin signaling pathways

MB Taylor, MJ Dunham - 2024 - depts.washington.edu
Caffeine is an alkaloid produced by plants including coffee and cacao. It is desirable for its
effects as a stimulant and also inhibits the master signaling regulator target of rapamycin …