Biological roles of glycans
A Varki - Glycobiology, 2017 - academic.oup.com
Simple and complex carbohydrates (glycans) have long been known to play major
metabolic, structural and physical roles in biological systems. Targeted microbial binding to …
metabolic, structural and physical roles in biological systems. Targeted microbial binding to …
The type II secretion system: biogenesis, molecular architecture and mechanism
KV Korotkov, M Sandkvist, WGJ Hol - Nature Reviews Microbiology, 2012 - nature.com
Many Gram-negative bacteria use the sophisticated type II secretion system (T2SS) to
translocate a wide range of proteins from the periplasm across the outer membrane. The …
translocate a wide range of proteins from the periplasm across the outer membrane. The …
Carbohydrate-binding domains: multiplicity of biological roles
Insoluble polysaccharides can be degraded by a set of hydrolytic enzymes formed by
catalytic modules appended to one or more non-catalytic carbohydrate-binding modules …
catalytic modules appended to one or more non-catalytic carbohydrate-binding modules …
Sialidases from gut bacteria: a mini-review
Sialidases are a large group of enzymes, the majority of which catalyses the cleavage of
terminal sialic acids from complex carbohydrates on glycoproteins or glycolipids. In the …
terminal sialic acids from complex carbohydrates on glycoproteins or glycolipids. In the …
Metagenomic characterization of the enhanced performance of anaerobic fermentation of waste activated sludge with CaO2 addition at ambient temperature: fatty acid …
This study investigated the chemical and genetic mechanisms of anaerobic fermentation of
waste activated sludge (WAS) with CaO 2 addition at ambient temperature. The microbial …
waste activated sludge (WAS) with CaO 2 addition at ambient temperature. The microbial …
Host sialoglycans and bacterial sialidases: a mucosal perspective
Sialic acids are nine‐carbon‐backbone sugars that occupy outermost positions on
vertebrate cells and secreted sialoglycoproteins. These negatively charged hydrophilic …
vertebrate cells and secreted sialoglycoproteins. These negatively charged hydrophilic …
Role of adherent and invasive Escherichia coli in Crohn's disease: lessons from the postoperative recurrence model
A Buisson, H Sokol, N Hammoudi, X Treton, M Nachury… - Gut, 2023 - gut.bmj.com
Objective We used the postoperative recurrence model to better understand the role of
adherent and invasive Escherichia coli (AIEC) bacteria in Crohn's disease (CD), taking …
adherent and invasive Escherichia coli (AIEC) bacteria in Crohn's disease (CD), taking …
Computational screening and MM/GBSA-based MD simulation studies reveal the high binding potential of FDA-approved drugs against Cutibacterium acnes …
Cutibacterium acnes is an opportunistic pathogen linked with acne vulgaris, affecting 80–
90% of teenagers globally. On the leukocyte (WBCs) cell surface, the cell wall anchored …
90% of teenagers globally. On the leukocyte (WBCs) cell surface, the cell wall anchored …
Bacterial neuraminidase facilitates mucosal infection by participating in biofilm production
G Soong, A Muir, MI Gomez, J Waks… - The Journal of …, 2006 - Am Soc Clin Investig
Many respiratory pathogens, including Hemophilus influenzae, Streptococcus pneumoniae,
and Pseudomonas aeruginosa, express neuraminidases that can cleave α2, 3-linked sialic …
and Pseudomonas aeruginosa, express neuraminidases that can cleave α2, 3-linked sialic …
The NanA Neuraminidase of Streptococcus pneumoniae Is Involved in Biofilm Formation
Streptococcus pneumoniae remains a major cause of bacteremia, pneumonia, and otitis
media despite vaccines and effective antibiotics. The neuraminidase of S. pneumoniae …
media despite vaccines and effective antibiotics. The neuraminidase of S. pneumoniae …