Uncovering the Multifaceted Roles of DDX21: Bridging Biological Insights and Medical Applications

J Shen, R Chen, K Guo, C Zhong… - Journal of Bio-X …, 2024 - spj.science.org
DDX21 belongs to the DEAD-box (DDX) family of helicases but deviates from the
characteristic sequence Asp–Glu–Ala–Asp (DEAD) to Asp–Glu–Val–Asp. In addition to the …

[HTML][HTML] Precore mutation enhances viral replication to facilitate persistent infection especially in HBeAg-negative patients

G Li, D Yang, X Liu, T Zhang, H Liu, J Zou, Z Xu… - Virologica Sinica, 2024 - Elsevier
Naturally occurred precore (PC, G1896A) and/or basal core promoter (BCP,
A1762T/G1764A) mutations are prevalent in chronic HBV-infected patients, especially those …

Manganese inhibits HBV transcription and promotes HBsAg degradation at non-toxic levels

Y Zhang, S Han, Y Li, Y Zhou, M Sun, M Hu… - International Journal of …, 2024 - Elsevier
Chronic hepatitis B virus (HBV) infection continues to pose a significant global health
challenge. However, therapeutic measures for a cure are lacking in clinical practice …

HBV PreC interacts with SUV39H1 to induce viral replication by blocking the proteasomal degradation of viral polymerase

L Hou, J Zhao, L Cai, L Jin, B Liu, S Li… - Journal of Medical …, 2024 - Wiley Online Library
Hepatitis B e antigen (HBeAg) seropositivity during the natural history of chronic hepatitis B
(CHB) is known to coincide with significant increases in serum and intrahepatic HBV DNA …

What is the real sword of HBV precore and basal core promoter mutations piercing the hepatocyte homeostasis: HBcAg or HBsAg?

G Li, X Liu, F Lu - Journal of medical virology, 2024 - pubmed.ncbi.nlm.nih.gov
What is the real sword of HBV precore and basal core promoter mutations piercing the hepatocyte
homeostasis: HBcAg or HBsAg? What is the real sword of HBV precore and basal core promoter …

[PDF][PDF] 血清乙型肝炎病毒表面抗原持续低水平与慢性乙型肝炎患者临床治愈相关进展

高林, 姜倩倩, 鲁凤民 - 临床内科杂志, 2023 - lcnkzz.com
血清HBsAg持续低水平与慢性乙型肝炎患者临床治愈相关进展 Page 1 [DOI]10.3969/j.issn.1001⁃9057.2023.12.002
http:/ /www.lcnkzz.com/CN/10.3969/j.issn.1001⁃9057.2023.12.002 ·综述与讲座· 血清HBsAg持续 …