[图书][B] Nelson's pediatric antimicrobial therapy

JS Bradley - 2012 - publications.aap.org
Welcome to the 29th edition of Nelson's Pediatric Antimicrobial Therapy, the third edition
written during the COVID-19 pandemic, which continues to significantly affect our lives and …

[HTML][HTML] A validated UHPLC–MS/MS method to quantify eight antibiotics in quantitative dried blood spots in support of pharmacokinetic studies in neonates

Q Liu, L Liu, Y Yuan, F Xie - Antibiotics, 2023 - mdpi.com
Objectives: Conduction of pharmacokinetic (PK) study in pediatric patients is challenging
due to blood sampling limits. The dried blood spots (DBS) method represents a potential …

Exposure-response relationships of metronidazole in infants: integration of electronic health record data with population pharmacokinetic modeling-derived exposure …

SJ Commander, DK Benjamin, H Wu… - The Pediatric …, 2023 - journals.lww.com
Background: Infants frequently receive metronidazole at variable doses and duration for
surgical site infection prophylaxis and treatment of intra-abdominal infections. Seizures are a …

Opportunistic dried blood spot sampling validates and optimizes a pediatric population pharmacokinetic model of metronidazole

RL Randell, SJ Balevic, RG Greenberg… - Antimicrobial Agents …, 2024 - Am Soc Microbiol
Pharmacokinetic models rarely undergo external validation in vulnerable populations such
as critically ill infants, thereby limiting the accuracy, efficacy, and safety of model-informed …

[图书][B] 2023 Nelson's Pediatric Antimicrobial Therapy

JD Nelson, American Academy of Pediatrics - 2023 - publications.aap.org
Completely updated and revised, the 29th edition of this best-selling reference provides
instant access to the latest recommendations for treatment of infectious diseases in children …

Association between neonatal intensive care unit medication safety practices, adverse events, and death

LE Miller, C DeRienzo, PB Smith, C Bose… - Journal of …, 2021 - nature.com
Objective Determine the associations between neonatal intensive care unit (NICU)
medication safety practices, laboratory-based adverse events (lab-AEs), and death. Study …

Age‐Dependent Abundance of CYP450 Enzymes Involved in Metronidazole Metabolism: Application to Pediatric PBPK Modeling

MM Parvez, A Thakur, A Mehrotra, S Stancil… - Clinical Pharmacology … - Wiley Online Library
The expression of cytochrome P450 (CYP) enzymes is highly variable and associated with
factors, such as age, genotype, sex, and disease states. In this study, quantification of …

[引用][C] Antibacterial Agents

JB Sauberan, MN Neely, JS Bradley - Principles and Practice of Pediatric …, 2023 - Elsevier