[HTML][HTML] Apoptotic cell death in disease—Current understanding of the NCCD 2023
I Vitale, F Pietrocola, E Guilbaud… - Cell Death & …, 2023 - nature.com
Apoptosis is a form of regulated cell death (RCD) that involves proteases of the caspase
family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis …
family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis …
[HTML][HTML] Polymer-and lipid-based nanocarriers for ocular drug delivery: current status and future perspectives
H Han, S Li, M Xu, Y Zhong, W Fan, J Xu, T Zhou… - Advanced Drug Delivery …, 2023 - Elsevier
Ocular diseases seriously affect patients' vision and life quality, with a global morbidity of
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …
[HTML][HTML] A new era in ocular therapeutics: advanced drug delivery systems for uveitis and neuro-ophthalmologic conditions
KY Wu, K Tan, D Akbar, MY Choulakian, SD Tran - Pharmaceutics, 2023 - mdpi.com
The eye's intricate anatomical barriers pose significant challenges to the penetration,
residence time, and bioavailability of topically applied medications, particularly in managing …
residence time, and bioavailability of topically applied medications, particularly in managing …
[HTML][HTML] Centenarian-Sourced Lactobacillus casei Combined with Dietary Fiber Complex Ameliorates Brain and Gut Function in Aged Mice
M Ren, H Li, Z Fu, Q Li - Nutrients, 2022 - mdpi.com
Dietary intervention could modulate age-related neurological disorders via the gut–brain
axis. The potential roles of a probiotic and the dietary fiber complex (DFC) on brain and gut …
axis. The potential roles of a probiotic and the dietary fiber complex (DFC) on brain and gut …
[HTML][HTML] Nanomedicine and drug delivery to the retina: Current status and implications for gene therapy
Blindness affects more than 60 million people worldwide. Retinal disorders, including age-
related macular degeneration (AMD), diabetic retinopathy (DR), and glaucoma, are the …
related macular degeneration (AMD), diabetic retinopathy (DR), and glaucoma, are the …
[HTML][HTML] Use of gene therapy for optic nerve protection: Current concepts
K Xu, L Yu, Z Wang, P Lin, N Zhang, Y Xing… - Frontiers in …, 2023 - frontiersin.org
Gene therapy has become an essential treatment for optic nerve injury (ONI) in recent years,
and great strides have been made using animal models. ONI, which is characterized by the …
and great strides have been made using animal models. ONI, which is characterized by the …
[HTML][HTML] Advanced gene nanocarriers/scaffolds in nonviral-mediated delivery system for tissue regeneration and repair
W Zhang, Y Hou, S Yin, Q Miao, K Lee, X Zhou… - Journal of …, 2024 - Springer
Tissue regeneration technology has been rapidly developed and widely applied in tissue
engineering and repair. Compared with traditional approaches like surgical treatment, the …
engineering and repair. Compared with traditional approaches like surgical treatment, the …
[HTML][HTML] Innovative strategies for drug delivery to the ocular posterior segment
A Gabai, M Zeppieri, L Finocchio, C Salati - Pharmaceutics, 2023 - mdpi.com
Innovative and new drug delivery systems (DDSs) have recently been developed to vehicle
treatments and drugs to the ocular posterior segment and the retina. New formulations and …
treatments and drugs to the ocular posterior segment and the retina. New formulations and …
Fostering the unleashing potential of nanocarriers-mediated delivery of ocular therapeutics
Ocular delivery is the most challenging aspect in the field of pharmaceutical research. The
major hurdle for the controlled delivery of drugs to the eye includes the physiological static …
major hurdle for the controlled delivery of drugs to the eye includes the physiological static …
Apoptosis in glaucoma: A new direction for the treatment of glaucoma
Q Xia, D Zhang - Molecular Medicine Reports, 2024 - spandidos-publications.com
Glaucoma is a group of progressive optic nerve disorders characterized by the loss of retinal
ganglion cells, a thinner retinal nerve fibre layer and cupping of the optic disk. Apoptosis is a …
ganglion cells, a thinner retinal nerve fibre layer and cupping of the optic disk. Apoptosis is a …