Hemocompatibility challenge of membrane oxygenator for artificial lung technology
The artificial lung (AL) technology is one of the membrane-based artificial organs that partly
augments lung functions, ie blood oxygenation and CO 2 removal. It is generally employed …
augments lung functions, ie blood oxygenation and CO 2 removal. It is generally employed …
Commercial and novel anticoagulant ECMO coatings: a review
C Zhao, K Sheng, T Bao, T Shi, P Liu, Y Yan… - Journal of Materials …, 2023 - pubs.rsc.org
Extracorporeal membrane oxygenation (ECMO) is an invasive and last-resort treatment for
circulatory and respiratory failure. Prolonged ECMO support can disrupt the coagulation and …
circulatory and respiratory failure. Prolonged ECMO support can disrupt the coagulation and …
[HTML][HTML] Superamphiphobic blood-repellent surface modification of porous fluoropolymer membranes for blood oxygenation applications
Biomedical gas exchange membranes used for blood oxygenation, including extracorporeal
membrane oxygenators (ECMO) and artificial lung technology, have suffered from the …
membrane oxygenators (ECMO) and artificial lung technology, have suffered from the …
Mechanisms for Reduced Fibrin Clot Formation on Liquid‐Infused Surfaces
Biomedical devices are prone to blood clot formation (thrombosis), and liquid‐infused
surfaces (LIS) are effective in reducing the thrombotic response. However, the mechanisms …
surfaces (LIS) are effective in reducing the thrombotic response. However, the mechanisms …
Development and Blood Compatibility of a Stable and Bioactive Metal–Organic Framework Composite Coating for Blood-Circulation Tubing
AC Melvin, TV Wick, Y Zang, GT Harea… - ACS Biomaterials …, 2022 - ACS Publications
Medical devices that require substantial contact between blood and a foreign surface would
be dramatically safer if constructed from materials that prevent clot formation and …
be dramatically safer if constructed from materials that prevent clot formation and …
Enhanced Anticoagulation of Hierarchy Liquid Infused Surfaces in Blood Flow
S Zhang, Y Wang, K Meng, X Zheng, Y Li… - ACS Applied Materials …, 2023 - ACS Publications
Liquid infused surfaces (LIS) hold remarkable potential in anticoagulation. However, liquid
loss of LIS in the bloodstream remains a challenge toward its clinical application. Here …
loss of LIS in the bloodstream remains a challenge toward its clinical application. Here …
Extracorporeal life support without systemic anticoagulation: a nitric oxide-based non-thrombogenic circuit for the artificial placenta in an ovine model
BP Fallon, O Lautner-Csorba, TC Major, G Lautner… - Pediatric …, 2024 - nature.com
Background Clinical translation of the extracorporeal artificial placenta (AP) is impeded by
the high risk for intracranial hemorrhage in extremely premature newborns. The Nitric Oxide …
the high risk for intracranial hemorrhage in extremely premature newborns. The Nitric Oxide …
Design Optimization of Perfluorinated Liquid‐Infused Surfaces for Blood‐Contacting Applications
Tethered‐liquid perfluorocarbon (TLP) coatings show promise for blood‐contacting medical
device applications to reduce blood adhesion and delay thrombosis. However, their …
device applications to reduce blood adhesion and delay thrombosis. However, their …
Robust, Scalable Microfluidic Manufacturing of RNA–Lipid Nanoparticles Using Immobilized Antifouling Lubricant Coating
YH Hwang, SJ Shepherd, D Kim, AJ Mukalel… - ACS …, 2024 - ACS Publications
Despite the numerous advantages demonstrated by microfluidic mixing for RNA-loaded lipid
nanoparticle (RNA-LNP) production over bulk methods, such as precise size control …
nanoparticle (RNA-LNP) production over bulk methods, such as precise size control …
Perfluorocarbons in research and clinical practice: a narrative review
G Nocentini, G MacLaren, R Bartlett, D De Luca… - Asaio …, 2023 - journals.lww.com
Perfluorocarbons (PFCs) are organic liquids derived from hydrocarbons in which some of
the hydrogen atoms have been replaced by fluorine atoms. They are chemically and …
the hydrogen atoms have been replaced by fluorine atoms. They are chemically and …