Antiplatelet drugs: antithrombotic therapy and prevention of thrombosis: American College of Chest Physicians evidence-based clinical practice guidelines

JW Eikelboom, J Hirsh, FA Spencer, TP Baglin, JI Weitz - Chest, 2012 - Elsevier
The article describes the mechanisms of action, pharmacokinetics, and pharmacodynamics
of aspirin, dipyridamole, cilostazol, the thienopyridines, and the glycoprotein IIb/IIIa …

The cardiovascular disease continuum validated: clinical evidence of improved patient outcomes: part I: Pathophysiology and clinical trial evidence (risk factors …

VJ Dzau, EM Antman, HR Black, DL Hayes… - Circulation, 2006 - Am Heart Assoc
Fifteen years ago, a panel of experts representing the full spectrum of cardiovascular
disease (CVD) research and practice assembled at a workshop to examine the state of …

Prevalence of conventional risk factors in patients with coronary heart disease

UN Khot, MB Khot, CT Bajzer, SK Sapp, EM Ohman… - Jama, 2003 - jamanetwork.com
ContextIt is commonly suggested that more than 50% of patients with coronary heart disease
(CHD) lack any of the conventional risk factors (cigarette smoking, diabetes, hyperlipidemia …

Guidelines for the diagnosis and treatment of non-ST-segment elevation acute coronary syndromes: The Task Force for the Diagnosis and Treatment of Non-ST …

JP Bassand, CW Hamm, D Ardissino… - European heart …, 2007 - academic.oup.com
The content of these European Society of Cardiology (ESC) Guidelines has been published
for personal and educational use only. No commercial use is authorized. No part of the ESC …

Guidelines for percutaneous coronary interventions: the Task Force for Percutaneous Coronary Interventions of the European Society of Cardiology

S Silber, P Albertsson, FF Avilés… - European heart …, 2005 - academic.oup.com
In patients with stable CAD, PCI can be considered a valuable initial mode of
revascularization in all patients with objective large ischaemia in the presence of almost …

Platelet glycoprotein IIb/IIIa inhibitors in acute coronary syndromes: a meta-analysis of all major randomised clinical trials

E Boersma, RA Harrington, DJ Moliterno, H White… - The Lancet, 2002 - thelancet.com
Summary Background Platelet glycoprotein IIb/IIIa inhibitors have been shown to reduce
cardiac complications in patients undergoing percutaneous coronary intervention. The …

[PDF][PDF] Management of acute coronary syndromes in patients presenting without persistent ST-segment elevation

M Bertrand, M Simoons, K Fox, L Wallentin… - European heart …, 2002 - repub.eur.nl
The clinical presentations of ischaemic heart disease include stable angina pectoris, silent
ischaemia, unstable angina, myocardial infarction, heart failure, and sudden death. For …

Platelet-active drugs: the relationships among dose, effectiveness, and side effects: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy

C Patrono, B Coller, GA FitzGerald, J Hirsh, G Roth - Chest, 2004 - Elsevier
This article discusses platelet active drugs as part of the Seventh American College of Chest
Physicians Conference on Antithrombotic and Thrombolytic Therapy: Evidence-Based …

Coronary angioplasty with or without stent implantation for acute myocardial infarction

CL Grines, DA Cox, GW Stone, E Garcia… - … England Journal of …, 1999 - Mass Medical Soc
Background Coronary-stent implantation is frequently performed for treatment of acute
myocardial infarction. However, few studies have compared stent implantation with primary …

Inhibition of platelet glycoprotein IIb/IIIa with eptifibatide in patients with acute coronary syndromes

PURSUIT Trial Investigators - New England Journal of Medicine, 1998 - Mass Medical Soc
Background Aggregation of platelets is the pathophysiologic basis of the acute coronary
syndromes. Eptifibatide, a synthetic cyclic heptapeptide, is a selective high-affinity inhibitor …