Low back pain (LBP) is a common health issue worldwide with a huge economic burden on
healthcare systems. In the United States alone, the cost is estimated to be $100 billion each …

Mechanical robustness is an essential consideration in the development of hydrogel
platforms for bone regeneration, and despite significant advances in the field of injectable …

Abstract Numerous spine Finite Element (FE) models have been developed to assess spinal
tolerances, spinal loadings and low back pain-related issues. However, justified …

Introduction Interbody cages are currently being used to address diseases of the vertebra
requiring surgical stabilization. Titanium cages were first introduced in 1988 …

Spine is the most common site for bone metastases. The evaluation of the mechanical
competence and failure location in metastatic vertebrae is a biomechanical and clinical …

Natural intervertebral disks (IVDs) exhibit distinctive anisotropic mechanical support and
dissipation performances due to their well-developed special microstructures. As the intact …

This article presents an effort toward building an artificial intelligence (AI) assisted
framework, coined ReconGAN, for creating a realistic digital twin of the human vertebra and …

Introduction Up to one in five will suffer from osteoporotic vertebral fracture within their
lifetime. Accurate fracture prediction poses challenges using bone mineral density (BMD) …

Despite advances in biomaterials research, there is no ideal device for replacing weight‐
bearing soft tissues like menisci or intervertebral discs due to poor integration with tissues …

The structural performance of a vertebra can be significantly undermined if it develops a
tumour, that could even lead to the vertebra's structural collapse. In cancers with a high …