Calcium homeostasis plays an essential role in maintaining excitation–contraction coupling
(ECC) in cardiomyocytes, including calcium release, recapture, and storage. Disruption of …

Ischemic stroke is caused by a thromboembolic occlusion of a major cerebral artery, with the
impaired blood flow triggering neuroinflammation and subsequent neuronal damage. Both …

Ischemic stroke (IS) is a multifactorial disease caused by the interaction of multiple
environmental and genetic risk factors, and it is the most common cause of disability. The …

Presently, the treatment options for ischemic stroke (IS) are limited due to the complicated
pathological process of the disease. Chuanxiong Rhizome (CR), also known as …

Background After ischemic stroke (IS), peripheral leukocytes infiltrate the damaged region
and modulate the response to injury. Peripheral blood cells display distinctive gene …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with progressive
paralysis of limbs and bulb in patients, the cause of which remains unclear. Accumulating …

Ischemic stroke is associated with a high mortality rate, and effective treatment strategies are
currently lacking. In this study, we aimed to develop a novel nano delivery system to treat …

Stroke is a cerebrovascular event with cerebral blood flow interruption which is caused by
occlusion or bursting of cerebral vessels. At present, the main methods in treating stroke are …

Background The specific molecular mechanistic link between atherosclerotic plaques and
ischemic stroke (IS) is not clear. The aim of this study is to explore the potential molecular …

Abstract Purpose Vessel wall MRI (VW-MRI) can be used to evaluate the nature of
intracranial atherosclerosis (ICAS) plaque in vivo. Phosphodiesterase 4D (PDE4D) …