Intracellular membrane fusion is mediated in most cases by membrane-bridging complexes
of soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) …

The exocyst is an octameric protein complex that is implicated in the tethering of secretory
vesicles to the plasma membrane prior to SNARE-mediated fusion. Spatial and temporal …

The compartmentalization of eukaryotic cells is reliant on the fidelity of vesicle-mediated
intracellular transport. Vesicles deliver their cargo via membrane fusion, a process requiring …

The exocyst is a multisubunit protein complex that was first identified and characterized in
budding yeast. Later studies have demonstrated its conservation in eukaryotes, from plants …

The exocyst is a hetero-octameric complex that has been proposed to serve as the tethering
complex for exocytosis, although it remains poorly understood at the molecular level. Here …

Targeting of endomembrane transport containers is of the utmost importance for proper land
plant growth and development. Given the immobility of plant cells, localized membrane …

A major challenge for a molecular understanding of membrane trafficking has been the
elucidation of high-resolution structures of large, multisubunit tethering complexes that …

The soluble N-ethylmaleimide-sensitive factor-attachment protein receptors (SNAREs)
constitute the core machinery for membrane fusion during eukaryotic cell vesicular …

Most membrane fusion reactions in eukaryotic cells are mediated by multisubunit tethering
complexes (MTCs) and SNARE proteins. MTCs are much larger than SNAREs and are …

Fungal hyphae are among the most highly polarized cells. Hyphal polarized growth is
supported by tip-directed transport of secretory vesicles, which accumulate temporarily in a …