The constant failure of new neuroprotective therapies for ischemic stroke has partially halted
the search for new therapies in recent years, mainly because of the high investment risk …

Cerebral ischemia affects millions of people worldwide and survivors suffer from long-term
functional and cognitive deficits. While stroke and cardiac arrest are typically considered …

Background: RNA-binding motif protein 3 (RBM3) is a cold-induced marker of good
functional outcome of ischemic stroke that is promising as a protective target. Fibroblast …

Background and purpose The deleterious effect of hyperthermia on intracerebral
hemorrhage (ICH) has been studied. However, the results are not conclusive and new …

Changes in brain temperature have been reported to affect various brain functions.
However, little is known about the effects of temperature on the neural activity at the network …

RNA-binding motif protein 3 is a molecular marker of hypothermia that has proved
neuroprotective in neurodegenerative disease models. However, its relationship to the well …

The precise measurement of cell temperature and an in‐depth understanding of
thermogenic processes are critical in unraveling the complexities of cellular metabolism and …

Decades of animal research show therapeutic hypothermia (TH) to be potently
neuroprotective after cerebral ischemic injuries. While there have been some translational …

Therapeutic hypothermia (TH) is a potent neuroprotectant against multiple forms of brain
injury, but in some cases, prolonged cooling is needed. Such cooling protocols raise the risk …

The blood enzyme glutamate-oxaloacetate transaminase (GOT) has been postulated as an
effective therapeutic to protect the brain during stroke. To demonstrate its potential clinical …