[HTML][HTML] Mitochondria-associated membranes: A hub for neurodegenerative diseases

J Liu, J Yang - Biomedicine & Pharmacotherapy, 2022 - Elsevier
In eukaryotic cells, organelles could coordinate complex mechanisms of signaling
transduction metabolism and gene expression through their functional interactions. The …

[HTML][HTML] Mitofusins: from mitochondria to fertility

S Zhao, N Heng, H Wang, H Wang, H Zhang… - Cellular and Molecular …, 2022 - Springer
Germ cell formation and embryonic development require ATP synthesized by mitochondria.
The dynamic system of the mitochondria, and in particular, the fusion of mitochondria, are …

PACS-2 Ameliorates Tubular Injury by Facilitating Endoplasmic Reticulum–Mitochondria Contact and Mitophagy in Diabetic Nephropathy

C Li, L Li, M Yang, J Yang, C Zhao, Y Han, H Zhao… - Diabetes, 2022 - Am Diabetes Assoc
Mitochondria-associated endoplasmic reticulum membrane (MAM) may have a role in
tubular injury in diabetic nephropathy (DN), but the precise mechanism remains unclear …

[HTML][HTML] Melatonin: regulation of biomolecular condensates in neurodegenerative disorders

D Loh, RJ Reiter - Antioxidants, 2021 - mdpi.com
Biomolecular condensates are membraneless organelles (MLOs) that form dynamic,
chemically distinct subcellular compartments organizing macromolecules such as proteins …

[HTML][HTML] Mitophagy in atherosclerosis: from mechanism to therapy

Y Zhang, J Weng, L Huan, S Sheng, F Xu - Frontiers in Immunology, 2023 - frontiersin.org
Mitophagy is a type of autophagy that can selectively eliminate damaged and depolarized
mitochondria to maintain mitochondrial activity and cellular homeostasis. Several pathways …

Balancing life and death: BCL‐2 family members at diverse ER–mitochondrial contact sites

RE Means, SG Katz - The FEBS journal, 2022 - Wiley Online Library
The outer mitochondrial membrane is a busy place. One essential activity for cellular
survival is the regulation of membrane integrity by the BCL‐2 family of proteins. Another …

TRPV4 regulates mitochondrial Ca2+-status and physiology in primary murine T cells based on their immunological state

TK Acharya, S Kumar, TP Rokade, YT Chang… - Life Sciences, 2023 - Elsevier
T cell activation process is critically affected by temperature and intracellular Ca 2+-
signalling. Yet, the nature and the key molecules involved in such complex Ca 2+-signalling …

[HTML][HTML] Apolipoproteins L1 and L3 control mitochondrial membrane dynamics

L Lecordier, P Heo, JH Graversen, D Hennig… - Cell reports, 2023 - cell.com
Summary Apolipoproteins L1 and L3 (APOLs) are associated at the Golgi with the
membrane fission factors phosphatidylinositol 4-kinase-IIIB (PI4KB) and non-muscular …

Mitofusin-2: functional switch between mitochondrial function and neurodegeneration

PG Kulkarni, VM Mohire, PK Bhaisa, MM Joshi… - Mitochondrion, 2023 - Elsevier
Mitochondria are highly dynamic organelles known to play role in the regulation of several
cellular biological processes. However, their dynamics such as number, shape, and …

[HTML][HTML] Mitochondria have made a long evolutionary path from ancient bacteria immigrants within eukaryotic cells to essential cellular hosts and key players in human …

A Atlante, D Valenti - Current Issues in Molecular Biology, 2023 - mdpi.com
Mitochondria have made a long evolutionary path from ancient bacteria immigrants within
the eukaryotic cell to become key players for the cell, assuming crucial multitasking skills …