Molecular profiling of tumor biopsies plays an increasingly important role not only in cancer
research, but also in the clinical management of cancer patients. Multi-omics approaches …

Immune checkpoint inhibitor treatment has the potential to prolong survival in non-small cell
lung cancer (NSCLC), however, some of the patients develop resistance following initial …

Whole exome sequencing (WES) enables the analysis of all protein coding sequences in
the human genome. This technology enables the investigation of cancer-related genetic …

We developed grenepipe, an all-in-one Snakemake workflow to streamline the data
processing from raw high-throughput sequencing data of individuals or populations to …

Genetic transformation has been an effective technology for improving the agronomic traits
of maize. However, it is highly reliant on the use of embryonic callus (EC) and shows a …

Background Molecular precision oncology is an emerging practice to improve cancer
therapy by decreasing the risk of choosing treatments that lack efficacy or cause adverse …

The accurate identification of somatic mutations has become a pivotal component of tumor
profiling and precision medicine. In molecular diagnostics laboratories, somatic mutation …

This humble effort highlights the intricate details of metagenomics in a simple, poetic, and
rhythmic way. The paper enforces the significance of the research area, provides details …

Despite the tremendous increase in omics data generated by modern sequencing
technologies, their analysis can be tricky and often requires substantial expertise in …

Simple Summary Tumours consist of multiple groups of similar cells resulting from differing
evolutionary trajectories, ie, subclones. These subclones are prevalent in clear cell renal cell …