Salivary gland function, development, and regeneration

AM Chibly, MH Aure, VN Patel… - Physiological …, 2022 - journals.physiology.org
Salivary glands produce and secrete saliva, which is essential for maintaining oral health
and overall health. Understanding both the unique structure and physiological function of …

RET signaling pathway and RET inhibitors in human cancer

AT Regua, M Najjar, HW Lo - Frontiers in Oncology, 2022 - frontiersin.org
Rearranged during transfection (RET) receptor tyrosine kinase was first identified over thirty
years ago as a novel transforming gene. Since its discovery and subsequent pathway …

Salivary gland organoid culture maintains distinct glandular properties of murine and human major salivary glands

YJ Yoon, D Kim, KY Tak, S Hwang, J Kim… - Nature …, 2022 - nature.com
Salivary glands that produce and secrete saliva, which is essential for lubrication, digestion,
immunity, and oral homeostasis, consist of diverse cells. The long-term maintenance of …

Enhancer hijacking activates oncogenic transcription factor NR4A3 in acinic cell carcinomas of the salivary glands

F Haller, M Bieg, R Will, C Körner… - Nature …, 2019 - nature.com
The molecular pathogenesis of salivary gland acinic cell carcinoma (AciCC) is poorly
understood. The secretory Ca-binding phosphoprotein (SCPP) gene cluster at 4q13 …

Three‐year cytohistological correlation of salivary gland FNA cytology at a tertiary center with the application of the Milan system for risk stratification

M Rohilla, P Singh, A Rajwanshi, N Gupta… - Cancer …, 2017 - Wiley Online Library
BACKGROUND Fine‐needle aspiration (FNA) cytology of salivary glands is a well‐
established technique that plays a critical role in the preoperative diagnosis of lesions. A risk …

Contemporary management of benign and malignant parotid tumors

J Thielker, M Grosheva, S Ihrler, A Wittig… - Frontiers in …, 2018 - frontiersin.org
To report the standard of care, interesting new findings and controversies about the
treatment of parotid tumors. Relevant and actual studies were searched in PubMed and …

Salivary gland malignancies

ER Carlson, T Schlieve - Oral and Maxillofacial …, 2019 - oralmaxsurgery.theclinics.com
Tumors of the salivary glands collectively represent a very diverse and heterogeneous
group of neoplasms with complex clinicopathologic characteristics and distinct biological …

Minor salivary gland tumors of the head and neck—Memorial Sloan Kettering experience: incidence and outcomes by site and histological type

AJ Hay, J Migliacci, D Karassawa Zanoni, M McGill… - Cancer, 2019 - Wiley Online Library
Background Minor salivary gland carcinomas of the head and neck are rare cancers with
variable clinical behavior. This study explored the incidence, pathology, clinical behavior …

Targeted therapy, chemotherapy, immunotherapy and novel treatment options for different subtypes of salivary gland cancer

SK Mueller, M Haderlein, S Lettmaier… - Journal of Clinical …, 2022 - mdpi.com
Surgical resection remains the first line treatment for salivary gland cancer (SGC). In the
case of locally advanced disease, surgery is followed by adjuvant radiotherapy. Surgical …

Salivary gland tumors in a Brazilian population: A 20-year retrospective and multicentric study of 2292 cases

LP da Silva, MS Serpa, SK Viveiros, DAC Sena… - Journal of Cranio …, 2018 - Elsevier
Purpose Neoplasms of the salivary glands comprise more than thirty subtypes of lesions
with various clinical behaviors. The present study aimed to describe the incidence and main …