Autoantibodies in systemic lupus erythematosus: From immunopathology to therapeutic target
H Lou, GS Ling, X Cao - Journal of autoimmunity, 2022 - Elsevier
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by multiple
organ inflammatory damage and wide spectrum of autoantibodies. The autoantibodies …
organ inflammatory damage and wide spectrum of autoantibodies. The autoantibodies …
Complement activation by (auto-) antibodies
NA Daha, NK Banda, A Roos, FJ Beurskens… - Molecular …, 2011 - Elsevier
The complement system is a key part of the innate immune system and plays an important
role in the clearance of pathogens and apoptotic cells upon its activation. It is well known …
role in the clearance of pathogens and apoptotic cells upon its activation. It is well known …
Complement in lupus nephritis: new perspectives
L Bao, PN Cunningham, RJ Quigg - Kidney Diseases, 2015 - karger.com
Background: Systemic lupus erythematosus (SLE) is an autoimmune disorder caused by
loss of tolerance to self-antigens, the production of autoantibodies and deposition of …
loss of tolerance to self-antigens, the production of autoantibodies and deposition of …
Complement component 3 inhibition by an antioxidant is neuroprotective after cerebral ischemia and reperfusion in mice
Oxidative stress after stroke is associated with the inflammatory system activation in the
brain. The complement cascade, especially the degradation products of complement …
brain. The complement cascade, especially the degradation products of complement …
Protein microarray applications: autoantibody detection and posttranslational modification
The discovery of DNA microarrays was a major milestone in genomics; however, it could not
adequately predict the structure or dynamics of underlying protein entities, which are the …
adequately predict the structure or dynamics of underlying protein entities, which are the …
[HTML][HTML] Immune complex signatures of patients with active and inactive SLE revealed by multiplex protein binding analysis on antigen microarrays
Systemic lupus erythematosus is characterized by dysfunctional clearance of apoptotic
debris and the development of pathogenic autoantibodies. While the complement system is …
debris and the development of pathogenic autoantibodies. While the complement system is …
Suppression of autoreactive T and B lymphocytes by anti-annexin A1 antibody in a humanized NSG murine model of systemic lupus erythematosus
N Mihaylova, P Chipinski, S Bradyanova… - Clinical & …, 2020 - academic.oup.com
Systemic lupus erythematosus is a chronic inflammatory disease which involves multiple
organs. Self-specific B and T cells play a main role in the pathogenesis of lupus and have …
organs. Self-specific B and T cells play a main role in the pathogenesis of lupus and have …
[HTML][HTML] Why current quantitative serology is not quantitative and how systems immunology could provide solutions
J Prechl - Biologia Futura, 2021 - Springer
Determination of the presence of antibodies against infectious agents, self-antigens,
allogeneic antigens and environmental antigens is the goal of medical serology. Along with …
allogeneic antigens and environmental antigens is the goal of medical serology. Along with …
Annexin A1 as a target for managing murine pristane-induced systemic lupus erythematosus
N Mihaylova, S Bradyanova, P Chipinski, M Herbáth… - …, 2017 - Taylor & Francis
Systemic lupus erythematosus (SLE) is a polygenic pathological disorder which involves
multiple organs. Self-specific B cells play a main role in the lupus pathogenesis by …
multiple organs. Self-specific B cells play a main role in the lupus pathogenesis by …
Lupus progression deteriorates oogenesis quality in MRL/lpr mice
S Delimitreva, G Boneva, I Chakarova… - Immunologic …, 2024 - Springer
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the
activation of the immune response against self antigens. Numerous reproductive …
activation of the immune response against self antigens. Numerous reproductive …