Nociceptor inputs can trigger a prolonged but reversible increase in the excitability and
synaptic efficacy of neurons in central nociceptive pathways, the phenomenon of central …

The ABA pain guidelines were developed 14 years ago and have not been revised despite
evolution in the practice of burn care. A sub-committee of the American Burn Association's …

IMPLICATIONS: This meta-analysis assesses the ability of preemptive analgesic
interventions to attenuate postoperative pain scores, decrease supplemental postoperative …

Pain is one of the main postoperative adverse outcomes. Single analgesics, either opioid or
nonsteroidal antiinflammatory drugs (NSAIDs), are not able to provide effective pain relief …

The development of more effective methods of relieving pain associated with burn injury is a
major unmet medical need. Not only is acute burn injury pain a source of immense suffering …

Total knee replacement (TKR) produces severe postoperative pain. Peripheral nerve blocks
can be used as analgesic adjuncts for TKR, but the efficacy of femoral nerve blocks alone is …

Preemptive analgesia is an antinociceptive treatment that prevents the establishment of
altered central processing, which amplifies postoperative pain. The altered sensory …

Efficacy and Safety of Steroid Use for Postoperative Pain Re... : JBJS Efficacy and Safety of
Steroid Use for Postoperative Pain Relief: Update and Review of the Medical Literature : JBJS …

Rebound pain after regional anesthesia can be defined as transient acute postoperative
pain that ensues following resolution of sensory blockade, and is clinically significant, either …

Context.—Preemptive analgesia can decrease the sensitization of the central nervous
system that would ordinarily amplify subsequent nociceptive input, but a clear demonstration …